Obiettivo With this proposal I plan to dissect, at the genetic level, those circuits controlling goal-oriented movements in mice. In particular, we will focus on the very feature that makes goal-oriented movements so unique in the world of motor control, the spatial awareness of such movements, the fact that their execution is likely to obey a precise metric. I want to understand: (1) which neuronal circuits promote the initiation of targeted-movement and assess the genetic heterogeneity of these circuits. (2) Characterise the function of genetically identified circuit elements during movement execution, with the aim of understanding how the metric of motion is encoded. (3) Investigate how sensory maps and motor maps are aligned during development and probe their plasticity. In prospective (4), we aim to understand how changes in such circuits impinge on the development and evolution of innate behaviours such as predation. The French mathematician Henry Poincaré wrote that ‘The real space is motor space’. Embedded in this idea is the intimate relation between the perceptual encoding of space and motor execution. Accordingly, our research starts at the motor level and aims to move to the perceptual level. Campo scientifico natural sciencesbiological scienceszoologymammalogyprimatologynatural sciencesbiological sciencesgeneticsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesbiological sciencesbiological behavioural sciencesethologybiological interactionsnatural sciencescomputer and information sciencesartificial intelligencecomputational intelligence Programma(i) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Argomento(i) ERC-StG-2015 - ERC Starting Grant Invito a presentare proposte ERC-2015-STG Vedi altri progetti per questo bando Meccanismo di finanziamento ERC-STG - Starting Grant Istituzione ospitante UNITED KINGDOM RESEARCH AND INNOVATION Contribution nette de l'UE € 1 495 731,00 Indirizzo POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon Regno Unito Mostra sulla mappa Regione South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Tipo di attività Research Organisations Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 1 495 731,00 Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo netto dell'UE Espandi tutto Riduci tutto UNITED KINGDOM RESEARCH AND INNOVATION Regno Unito Contribution nette de l'UE € 1 495 731,00 Indirizzo POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon Mostra sulla mappa Regione South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Tipo di attività Research Organisations Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 1 495 731,00