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Life in Arsenic rich environments: a challenge or an opportunity?

Objective

Arsenic is a notorious toxin, and as such may have exerted a strong selective pressure on the distribution and evolution of life on Earth. Despite evidence supporting the high levels and prominent role of As on the primitive Earth, the essentiality and toxicity of As, and its impact on evolutionary processes remains unexplored. AsLife aims at taking a novel approach to assessing microbial As cycling by exploiting two linked «environments». The first are the microbial mats from High-Altitude Andean Lakes, where it is known that As concentrations are far above background levels. Specifically, living and diagenetically-modified microbial mats will be investigated using scanning hard X-ray nanoprobes emerging at synchrotron facilities. This non-invasive and non-destructive technique provides data on a sub-micrometer scale by which to tie physiological inference from trace metal(loid)s distribution and speciation patterns directly to the microfossil biomass. Thus, providing a means to understand the interplay between microbial metabolisms and bio-availability of trace metal(loid)s in living and fossil ecosystems. The second environment comprises laboratory cultures, using the sampling power of «adaptive laboratory evolution» to explore how microbes adapt and enhance As detoxification facing the extreme As levels present in Andean Lakes. These results will be discussed in light of genomic studies of As-rich microbiota performed by Argentinian colleagues.
During this project I will contact colleagues of the Jet Propulsion Laboratory in charge of the 2020 Mars Science Rover Mission and linked objective of returning samples for future analysis on Earth. I believe that my expertise in imaging and analyzing bio-geochemical proxies at multiple scales on a encapsulated geological sample can be relevant for contributing to the «Seek Signs of Life» Exploration Strategy of the 2020 Mission, thus establishing a strong and effective collaboration between EU and USA.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2015

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Coordinator

INSTITUT DE PHYSIQUE DU GLOBE DE PARIS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 173 076,00
Address
RUE JUSSIEU 1
75238 Paris
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 173 076,00
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