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Fluorescence lifetime optical biopsy system

Objective

The ultimate goal of this Fellowship is to train a talented researcher through a research project focused on the development of novel tools for the in vivo real-time assessment of the respiratory chain activity (NADH/FAD ratio) and mitochondrial dysfunction in tissues. This will be achieved by means of both laser fluorescence spectra and lifetime fluorescence data analysis, supplemented with additional optical measurements (laser Doppler flowmetry, tissue reflectance spectroscopy) in order to correct the impact of affecting factors (changes in blood perfusion, blood volume, blood oxygenation). The Fellow – Dr. Evgeny Zherebtsov – will be trained in biomedical optics, a fast growing field of science and medical application.He will receive access to a unique training experience at the host – Aston Institute of Photonics Technologies (AIPT), Aston University (Prof. E. Rafailov), and at academic and industrial secondment partners: University College London (Prof. Andrey Abramov), University of Bari, Italy (Prof. Annamaria De Luca), Axxam S.p.A. Italy (Dr Jean-Francois Rolland). The FORECAST outputs will be relevant to the EU life sciences sector by offering new cost-efficient technologies for real-time in vivo screening studies of metabolic activity in application of testing of new chemicals for efficacy and safety in small animals and test tubes during drug discovery and epithelium cancer diagnostics. The products transformed from the FORECAST outputs will contribute to the enhancement of EU scientific excellence.
The project brings together a talented young Fellow with a strong biomedical science and engineering background, and an internationally growing group of researchers at Aston University with expertise in the area of developing laser-based photonic devices for biomedical research and clinical diagnostics. The Fellow will be further supported by medical expert co-hosts who will help train the Fellow in key skills and support the translation process.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2015

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Coordinator

ASTON UNIVERSITY
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 195 454,80
Address
ASTON TRIANGLE
B4 7ET Birmingham
United Kingdom

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 195 454,80
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