Objective
Genetic selection for high yielding dairy cows has been associated with reduced fertility. Infertility remains the major reason for culling, decreasing longevity and reducing production efficiency. We propose that this trend could be reversed by identifying key genes involving reproductive function and selective breeding of more longlasting cows. The specific research objectives are: 1) to train the incoming researcher in bioinformatics methodologies related to analysis of large genomic datasets including SNP detection, genotyping, and evolutionary conserved DNA elements detection; 2) to use the methodologies to analyse dairy phenotypic and genomic data to highlight potential genic and regulatory regions of the cattle genome containing polymorphisms which are beneficial, with a particular focus on fertility; 3) to use appropriate tools to investigate the likely effects of both coding and regulatory variants on the expression of the candidate genes found in these regions; 4) to use pathway analysis to understand how the candidate genes may influence key molecular events and larger gene networks involved in reproductive phenotypes; 5) to recommend appropriate selection procedures to the EU dairy breeding industry to supplement current genomic methods. The project combines the expertise of Consiglio per la Ricerca in Agricoltura e l’analisi dell’Economia agraria, Italy (CREA) and the Royal Veterinary College, UK (RVC) in farm animal genetics and genomics and dairy cow production. The objectives will be met by the mobility of Dr L Buggiotti to the UK, where she will work closely alongside two senior RVC scientists, Dr DM Larkin and Professor DC Wathes. She will transfer this expertise back to CREA on her return. Both groups are experienced in knowledge transfer to the dairy industry and are committed to use the information generated to breed more fertile cows, so improving longevity and promoting sustainability of the EU dairy industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences computer and information sciences software
- agricultural sciences animal and dairy science dairy
- agricultural sciences animal and dairy science domestic animals animal husbandry
- natural sciences biological sciences zoology mammalogy
- natural sciences biological sciences genetics genomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-CAR - CAR – Career Restart panel
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
NW1 OTU London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.