Objective Biodegradable and biocompatible nanoparticles have high potential as viable carriers of active compounds in a broad range of applications for example for cosmetic ingredients as well as therapeutically active compounds such as vaccines, genes, drugs and other biomolecules (drug delivery). To advance current polymer nanoparticle technology we propose a novel nanomaterial platform based on synthetic polypeptide only comprising amino acid building blocks. The proposed system amalgamates the advantages of natural polymers (polypeptides) with the advantages of synthetic polymer chemistry, i.e. molecular weight and composition control. This will result in an innovative biodegradable nanomaterials platform highly adaptable to different cargoes and applications in the attractive Life Science sector. Feasibility will be investigated by loading and release studies of therapeutics for example small molecule drugs as well as hard-to-deliver next generation biopharmaceuticals. This highly interdisciplinary project between polymer, materials and pharmaceutical science will contribute to the advancement of this field addressing industry informed needs i.e. adaptable, nature-inspired nano-delivery systems at the forefront of fundamental and applied research. The applicants diverse experience in academic and industrially informed projects makes him an ideal match for this project. It provides a unique environment for the researcher to develop his skills supported by unique scientific and complementary training and accelerate his academic career in applied medicinal and biomaterial science. The dissemination of research results will target the professional audience as well the general public through outreach activities. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesnatural scienceschemical sciencespolymer sciencesmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesengineering and technologynanotechnologynano-materialsnatural scienceschemical sciencesorganic chemistryamines Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Call for proposal H2020-MSCA-IF-2015 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator ROYAL COLLEGE OF SURGEONS IN IRELAND Net EU contribution € 175 866,00 Address ST STEPHEN'S GREEN 123 2 Dublin Ireland See on map Region Ireland Northern and Western Border Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 175 866,00