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Diagnostic Test For The Differential Diagnosis of Bipolar Disorder and Major Depressive Disorder

Objective

Neuropsychiatric disorders contribute 13% to the global burden of disease and cost the European economy an estimated 789bn EUR a year. PsyOmics is a Cambridge-based biotechnology start-up focused on reducing this burden by providing scientifically-validated solutions that improve the prevention, diagnosis and treatment of psychiatric disorders. This project relates to the first clinical diagnostic that we intend to bring to market, a test to improve the diagnosis of bipolar disorder and major depressive disorder.
It is estimated that 33.4m people within the WHO European region suffer from major depression each year, and around 7m suffer from bipolar disorder. The separation of these two groups for appropriate treatment is very challenging because patients with an underlying bipolar disorder typically present with depressive symptoms that are indistinguishable from those of MDD. The result is that around 40% of all patients with an underlying bipolar disorder are initially misdiagnosed with depression and prescribed antidepressants, rather than mood stabiliser treatments. On average it takes over 7.5 years for the correct diagnosis to be reached.
There is no evidence to suggest that antidepressant monotherapies are effective in treating bipolar disorder and furthermore they are known to lead to an increased risk of anti-depressant induced mania, rapid cycling and suicide attempts among these patients, all of which lead to an increased rate of hospitalisation and healthcare costs.
Our clinical diagnostic will reduce this level of misdiagnosis by enabling GPs and Psychiatrists to efficiently identify those that have an underlying bipolar disorder amongst those that present with depressive symptoms.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

PSYOMICS LTD
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
20-22 WENLOCK ROAD
N1 7GU LONDON
United Kingdom

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
London Inner London — East Hackney and Newham
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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