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Multisensory Integration in Time and Space

Objective

In natural environments, the brain is typically bombarded with multisensory information. Animals must continually evaluate which of these multimodal cues should be associated with a single physical object, and which are separate. For example, when a rabbit hears footsteps and sees a blur, is the blur responsible for the footsteps, or are there two separate sources of danger? Animals use two types of information to make this decision: spatial correlations (are the footsteps and blur localized together) and temporal correlations (does the blur move in sync with the footsteps). Humans constantly perform these same operations. We use lip movements to help identify the words spoken by a friend, a subconscious process which becomes painfully apparent when watching a poorly dubbed movie. This may explain why psychological conditions such as autistic spectrum disorder and schizophrenia often present with deficits in audiovisual integration.

Despite the ethological and medical significance of multisensory integration, little is known about the underlying neural mechanisms. However, I believe the behavioral repertoire of the mouse, combined with new technological advances, provides an unprecedented opportunity to answer this fundamental research question. With recent developments in calcium imaging and optogenetic techniques, it is now possible to record and manipulate neural activity across the majority of mouse cortex. I will develop novel behavioral tasks for the mouse which require multisensory integration in space or time. By recording or perturbing cortical activity during these behaviors, I will determine the roles of individual neurons, neural populations, and cortical regions in multisensory integration.

I will perform these experiments in the Cortical Processing Laboratory at University College London, led by Professors Kenneth Harris and Matteo Carandini.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2015

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Coordinator

UNIVERSITY COLLEGE LONDON
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 183 454,80
Address
GOWER STREET
WC1E 6BT LONDON
United Kingdom

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 183 454,80
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