Objective
Having recently returned to the EU following Postdoctoral training in Australia, I hope to work as a MSCA Reintegration Fellow to tackle a devastating clinical orthopaedic challenge for which there is currently no effective treatment. Specifically, bisphosphonate (BP) associated atypical femoral fractures (AFFs) in osteoporotic patients which are associated with excruciating pain and high levels of morbidity and mortality. The scientific goal of this proposal is to integrate my tools in bone tissue engineering with the advanced drug delivery expertise of Prof. David Brayden’s group at University College Dublin (UCD) to develop a novel injectable therapeutic scaffold as a non-invasive treatment for AFFs. This proposal outlines an innovative research project that aims to implement a revolutionary strategy utilising Teriparatide (PTH-(1-34)) to target BP remobilisation away from AFF site and induce bone repair. In addition, a tissue engineering strategy will be employed that combines a regenerative, load bearing biomaterial for controlled local delivery of PTH(1-34) as a pioneering advance for AFF treatment. As a newly appointed academic, the training objective of this grant is to attain the requisite scientific and complementary skills to successfully develop an independent research programme. This will be achieved through the expert supervision and input of Prof. Brayden and backed up by colleagues in the lab and UCD staff training activities. In addition, by managing the project, I will further develop skills relating to planning and reporting, financial management, dissemination, patent filing and commercialisation. I will also avail of opportunities to recruit and supervise students on this project or related works. In summary, this grant will provide invaluable help to establish an independent research niche in active and emerging research fields, while equipping me with the skills needed as a newly appointed lecturer embarking on an independent research career.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- social sciences sociology demography mortality
- medical and health sciences medical biotechnology tissue engineering
- engineering and technology industrial biotechnology biomaterials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-RI - RI – Reintegration panel
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2 DUBLIN
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.