Objectif Speciation is a central process in evolution that involves the origin of barriers to gene flow between populations. Species are typically isolated by several barriers and assembly of multiple barriers separating the same populations seems to be critical to the evolution of strong reproductive isolation. Barriers resulting from direct selection can become coincident through a process of coupling while reinforcement can add barrier traits that are not under direct selection. In the presence of gene flow, these processes are opposed by recombination. While recent research using the latest sequencing technologies has provided much increased knowledge of patterns of differentiation and the genetic basis of local adaptation, it has so far added little to understanding of the coupling and reinforcement processes. In this project, I will focus on the accumulation of barriers to gene exchange and the processes underlying increasing reproductive isolation. I will use the power of natural contact zones, combined with novel manipulative experiments, to separate the processes that underlie patterns of differentiation and introgression. The Littorina saxatilis model system allows me to do this with both local replication and a contrast between distinct spatial contexts on a larger geographic scale. I will use modelling to determine how processes interact and to investigate the conditions most likely to promote coupling and reinforcement. Overall, the project will provide major new insights into the speciation process, particularly revealing the requirements for progress towards complete reproductive isolation. Champ scientifique natural sciencesbiological sciencesevolutionary biology Mots‑clés speciation local adaptation Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Thème(s) ERC-ADG-2015 - ERC Advanced Grant Appel à propositions ERC-2015-AdG Voir d’autres projets de cet appel Régime de financement ERC-ADG - Advanced Grant Institution d’accueil THE UNIVERSITY OF SHEFFIELD Contribution nette de l'UE € 1 524 404,76 Adresse FIRTH COURT WESTERN BANK S10 2TN Sheffield Royaume-Uni Voir sur la carte Région Yorkshire and the Humber South Yorkshire Sheffield Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 1 524 404,76 Bénéficiaires (2) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire THE UNIVERSITY OF SHEFFIELD Royaume-Uni Contribution nette de l'UE € 1 524 404,76 Adresse FIRTH COURT WESTERN BANK S10 2TN Sheffield Voir sur la carte Région Yorkshire and the Humber South Yorkshire Sheffield Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 1 524 404,76 GOETEBORGS UNIVERSITET Suède Contribution nette de l'UE € 975 521,88 Adresse VASAPARKEN 405 30 Goeteborg Voir sur la carte Région Södra Sverige Västsverige Västra Götalands län Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 975 521,88