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IMPACT TB: Implementing proven community-based active case finding interventions in Vietnam and Nepal

Objective

The aim of this project is to assess the facilitators and barriers to scale-up of two proven active TB case finding and comprehensive patient care models in Vietnam and Nepal as examples of these low and lower-middle income country settings. We will use these data to develop an evidence-based framework for scale-up of implementation by the respective National TB Programs in consultation with relevant stakeholders and governments. This will facilitate programmatic adoption of realistic and optimised active case finding strategies by national TB control programmes.
We will compare two alternative implementation strategies in each country appropriate to the local level of current service delivery. For Vietnam, we will compare implementation using salaried employees with volunteer counsellors. For Nepal, we will compare two diagnostic testing strategies as a component of active case finding: traditional smear microscopy or the novel Xpert Omni molecular testing.
We will determine the health economic impact of active case detection under the different models and model the long-term epidemiologic impact and cost-effectiveness.
The research seeks to achieve the following objectives:
1) Implementation of active case finding with comprehensive patient support in 6 districts of Ho Chi Minh City, Vietnam detecting 1,450 additional cases in 2 years.
2) Implementation of active case finding with comprehensive patient support in 4 districts of the Central Development Region of Nepal, detecting 1,050 additional cases in 2 years.
3) Health economic evaluation of alternative implementation models in low (Nepal) and middle income (Vietnam) scenarios to inform policy.
4) Consultation with policy makers, stakeholders and end-users to evaluate facillatators and barriers to scale-up at health system and individual level and development of an evidence-based framework for scale-up for each country.
5) Transmission modelling of epidemic impact and long-term cost-effectiveness.

Fields of science (EuroSciVoc)

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RIA - Research and Innovation action

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Call for proposal

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(opens in new window) H2020-SC1-2016-2017

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Coordinator

LIVERPOOL SCHOOL OF TROPICAL MEDICINE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 225 000,00
Address
PEMBROKE PLACE
L3 5QA LIVERPOOL 3
United Kingdom

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 225 000,00

Participants (4)

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