IMPACT TBProject ID: 733174
IMPACT TB: Implementing proven community-based active case finding interventions in Vietnam and Nepal
Total cost:EUR 4 912 423,75
EU contribution:EUR 4 912 423,75
Coordinated in:United Kingdom
Topic(s):SC1-PM-21-2016 - Implementation research for scaling-up of evidence based innovations and good practice in Europe and low- and middle-income countries
Call for proposal:H2020-SC1-2016-RTDSee other projects for this call
Funding scheme:RIA - Research and Innovation action
The aim of this project is to assess the facilitators and barriers to scale-up of two proven active TB case finding and comprehensive patient care models in Vietnam and Nepal as examples of these low and lower-middle income country settings. We will use these data to develop an evidence-based framework for scale-up of implementation by the respective National TB Programs in consultation with relevant stakeholders and governments. This will facilitate programmatic adoption of realistic and optimised active case finding strategies by national TB control programmes.
We will compare two alternative implementation strategies in each country appropriate to the local level of current service delivery. For Vietnam, we will compare implementation using salaried employees with volunteer counsellors. For Nepal, we will compare two diagnostic testing strategies as a component of active case finding: traditional smear microscopy or the novel Xpert Omni molecular testing.
We will determine the health economic impact of active case detection under the different models and model the long-term epidemiologic impact and cost-effectiveness.
The research seeks to achieve the following objectives:
1) Implementation of active case finding with comprehensive patient support in 6 districts of Ho Chi Minh City, Vietnam detecting 1,450 additional cases in 2 years.
2) Implementation of active case finding with comprehensive patient support in 4 districts of the Central Development Region of Nepal, detecting 1,050 additional cases in 2 years.
3) Health economic evaluation of alternative implementation models in low (Nepal) and middle income (Vietnam) scenarios to inform policy.
4) Consultation with policy makers, stakeholders and end-users to evaluate facillatators and barriers to scale-up at health system and individual level and development of an evidence-based framework for scale-up for each country.
5) Transmission modelling of epidemic impact and long-term cost-effectiveness.
EU contribution: EUR 1 225 000
EU contribution: EUR 1 524 026,25
EU contribution: EUR 1 022 995
LAZIMPAT KATHMANDU WARD N 2
EU contribution: EUR 646 563,75
Nobels Vag 5
EU contribution: EUR 493 838,75
BENOORDENHOUTSEWEG 46 VAN BYLANDTHUIS
2596 BC DEN HAAG