Objectif The tremendous technological advance underlying the ongoing genomic revolution in the life sciences has profoundly transformed biological research over the last 10-15 years. The grand challenge ahead is to leverage experimental progress like high-throughput sequencing by developing effective tools for large scale data-based inference and optimization. The goals of INFERNET rely on the transfer of ideas and methods developed in recent years at the boundary between statistical physics and information theory into the world of quantitative biology. We aim at setting up a consortium characterized by a proven track-record of high-quality research in order to implement a highly integrated program leading from the design of new algorithms to concrete biological applications. The consortium will provide the optimal environment to nurture a generation of researchers that will drive new developments at the forefront of these challenging fields.The perimeter of each individual research activity will be delimited by: (a) the research themes characterized by the toolbox and methods developed and shared within INFERNET, (b) the choice of the application domains. Principal research themes covered by the consortium will be: (i) the inference of interaction networks from data, (ii) the analysis of static and dynamical processes on networks. Application domains can be broken down into four main areas: (i) the inference and modeling of multi-scale biological networks, (ii) the rational design of biological molecules, (iii) the quantitative study of cell energetics in proliferative regimes, (iv) the characterization of functional states of large-scale regulatory networks. Each individual research project will be a puzzle piece of the wider research project, as well as tailored to suit each researcher's scientific and professional development. Champ scientifique natural sciencesbiological sciencesbiochemistrybiomoleculessocial sciencespolitical sciencespolitical transitionsrevolutions Mots‑clés mathematical modeling statistical inference multi-scale molecular networks co-evolution metabolic networks regulatory networks molecular design protein-protein interactions Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Thème(s) MSCA-RISE-2016 - Research and Innovation Staff Exchange Appel à propositions H2020-MSCA-RISE-2016 Voir d’autres projets de cet appel Régime de financement MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinateur IIGM FOUNDATION Contribution nette de l'UE € 408 600,00 Adresse PIAZZA BERNINI 5 10138 Torino Italie Voir sur la carte Région Nord-Ovest Piemonte Torino Type d’activité Research Organisations Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 408 600,00 Participants (3) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire SORBONNE UNIVERSITE France Contribution nette de l'UE € 345 600,00 Adresse 21 RUE DE L'ECOLE DE MEDECINE 75006 Paris Voir sur la carte Région Ile-de-France Ile-de-France Paris Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 345 600,00 BEATSON INSTITUTE FOR CANCER RESEARCH LBG Participation terminée Royaume-Uni Contribution nette de l'UE € 99 135,00 Adresse SWITCHBACK ROAD GARSCUBE ESTATE G61 1BD Bearsden Voir sur la carte Région Scotland West Central Scotland East Dunbartonshire Type d’activité Research Organisations Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 99 135,00 ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Suisse Contribution nette de l'UE € 46 665,00 Adresse BATIMENT CE 3316 STATION 1 1015 Lausanne Voir sur la carte Région Schweiz/Suisse/Svizzera Région lémanique Vaud Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 46 665,00 Partenaires (2) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire Partenaire Les organisations partenaires contribuent à la mise en œuvre de l’action, mais ne signent pas la convention de subvention. UNIVERSIDAD DE LA HABANA Cuba Contribution nette de l'UE € 0,00 Adresse COLINA UNIVERSITARIA SAN LAZARO Y L 10400 Plaza Voir sur la carte Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 477 855,00 Partenaire Les organisations partenaires contribuent à la mise en œuvre de l’action, mais ne signent pas la convention de subvention. Universidad Nacional de General Sarmiento Argentine Contribution nette de l'UE € 0,00 Adresse Juan M. Gutierrez 1150 B 1613 GSX Los Polvorines - Provincia De Buenos Aires Voir sur la carte Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 194 985,00