Single Molecule Nanoscale Sensors for Improved Therapies and Diagnostics

Projektinformationen

NanoPD

ID Finanzhilfevereinbarung: 724300

DOI 10.3030/724300

EK-Unterschriftsdatum 27 März 2017

Startdatum 1 Oktober 2017

Enddatum 31 Dezember 2024

Finanziert unter

• EXCELLENT SCIENCE - European Research Council (ERC)

Gesamtkosten € 1 997 680,00

EU-Beitrag € 1 997 680,00

Koordiniert durch

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom

Ziel

One of the most significant challenges facing the healthcare community is the accurate and selective detection and quantification of trace levels of analyte. This can have enormous impact with numerous application, especially in the context of biosensing, where applications can range from early stage detection of disease to the identification of new markers amongst others. These challenges are compounded when the analysis of real samples or even complex mixtures are required. To address this need, single molecule or near single molecule methods are currently being heavily pursued which allows for the discrimination of events with low copy numbers by removing the “clouding” associated with ensemble averaging. Although strategies for detecting single molecules have existed for a number of years, efficient and cost-effective label-free methods without the need for chemical modification are lacking especially when considering smaller molecules directly in unprocessed clinical samples. As part of this proposal, I intend to address this limitation by developing new strategies in single molecule nanoscale sensing which will be both highly sensitive and selective for improved therapeutics and diagnostics applications.

Wissenschaftliches Gebiet

• engineering and technology › environmental biotechnology › biosensing
• social sciences › sociology › social issues › social inequalities
• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors

Schlüsselbegriffe

• Single molecule sensing
• nanopores
• biosensors
• Parkinson's disease
• dopamine
• diagnostics

Programm/Programme

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Thema/Themen

• ERC-2016-COG - ERC Consolidator Grant

Aufforderung zur Vorschlagseinreichung

ERC-2016-COG

Finanzierungsplan

ERC-COG - Consolidator Grant

Gastgebende Einrichtung

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

• Netto-EU-Beitrag: € 1 997 680,00
• Adresse: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD ; SW7 2AZ LONDON ; Vereinigtes Königreich
• Region: London › Inner London — West › Westminster
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: € 1 997 680,00

Begünstigte (1)

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

Vereinigtes Königreich

• Netto-EU-Beitrag: € 1 997 680,00
• Adresse: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD ; SW7 2AZ LONDON
• Region: London › Inner London — West › Westminster
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: € 1 997 680,00