Cel Light is a fascinating reagent for chemistry as it provides energy to drive reactions, but leaves no trace. In visible light photoredox catalysis the initial electron transfer from the excited dye to a substrate yields radical anion or radical intermediates, which dominate the subsequent chemistry. Carbanions, which are the most important nucleophiles in organic chemistry, are typically not available from photocatalysis. The project PHAROS aims to overcome the current limitation of visible light photocatalysis to radical chemistry and extend its use to carbon nucleophiles. To obtain carbanions for organic synthesis using visible light, we propose three specific project tasks:1) We develop the next generation of visible light photocatalysts extending the current energetic limit of bond activation required for carbanion generation. This task is based on our recently developed consecutive photoinduced electron transfer (conPET) strategy accumulating the energy of more than one photon for synthesis. Now, the reduction power is further increased reaching potentials of alkali metals and allowing sequential two-electron transfers as needed for preparing carbanions.2) This technology is then used to generate carbanions from neutral starting materials by visible light photoinduced one- or two-electron transfer. The concept allows a light-driven synthetic carbanion chemistry without the stoichiometric use of reducing reagents, such as magnesium, zinc or lithium.3) Faster and cleaner reactions, longer catalyst lifetimes and selective photocatalytic sequences are achieved by sensitized photocatalysts and pulsed light excitation. This will enhance the overall energy efficiency of photoredox catalysis facilitating practical applications.The energy of visible light provides the redox energy to generate carbanions for organic synthesis and thereby broadens the synthetic use of the most abundant and sustainable energy source on earth, visible light. Dziedzina nauki natural scienceschemical sciencescatalysisphotocatalysisnatural scienceschemical sciencesorganic chemistrynatural scienceschemical sciencesinorganic chemistryalkali metalsnatural scienceschemical sciencesinorganic chemistryalkaline earth metalsnatural sciencesphysical sciencestheoretical physicsparticle physicsphotons Słowa kluczowe Carbanion electron transfer photoredox catalysis visible light Program(-y) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Temat(-y) ERC-2016-ADG - ERC Advanced Grant Zaproszenie do składania wniosków ERC-2016-ADG Zobacz inne projekty w ramach tego zaproszenia System finansowania ERC-ADG - Advanced Grant Instytucja przyjmująca UNIVERSITAET REGENSBURG Wkład UE netto € 2 458 200,00 Adres UNIVERSITATSSTRASSE 31 93053 Regensburg Niemcy Zobacz na mapie Region Bayern Oberpfalz Regensburg, Kreisfreie Stadt Rodzaj działalności Higher or Secondary Education Establishments Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Uczestnictwo w unijnych programach w zakresie badań i innowacji Opens in new window sieć współpracy HORIZON Opens in new window Koszt całkowity € 2 458 200,00 Beneficjenci (1) Sortuj alfabetycznie Sortuj według wkładu UE netto Rozwiń wszystko Zwiń wszystko UNIVERSITAET REGENSBURG Niemcy Wkład UE netto € 2 458 200,00 Adres UNIVERSITATSSTRASSE 31 93053 Regensburg Zobacz na mapie Region Bayern Oberpfalz Regensburg, Kreisfreie Stadt Rodzaj działalności Higher or Secondary Education Establishments Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Uczestnictwo w unijnych programach w zakresie badań i innowacji Opens in new window sieć współpracy HORIZON Opens in new window Koszt całkowity € 2 458 200,00
