Objetivo Presbyopia, the age-related loss of the ability of the eye to focus near and far objects, affects 1.2 billion people in the world. While there are a number of corrections for presbyopia available (near and progressive spectacles, monovision or multifocal lenses) none of these restore the dynamic focusing capability of the young crystalline lens. Replacing of the rigid crystalline lens in the aged eye by a shape-changing artificial lens able to respond an accommodative demand, therefore restoring accommodation in the aging eye, will undoubtedly increase the quality of vision, quality of life and productivity of millions of presbyopes worldwide.Presbyopia ERC Advanced Grant Presbyopia investigates basic mechanisms of the crystalline lens accommodation, to propose nature-inspired IOL designs to correct presbyopia. Imaging technologies developed during the project have allowed imaging-based quantification of the crystalline lens structure and its change with accommodation, aging and treatment. Knowledge gathered using these technologies, and developments combining optics, biomechanics, biomaterials and photo-chemistry have allowed a new concept for an accommodating IOL, of which the first prototypes have been manufactured and tested, therefore materializing the ultimate goal of the Presbyopia ERC AdG grant. This research has allowed to propose, develop and test a novel surface-change accommodating IOL, and a disruptive photo-activated method to transmit the forces from the eye muscle into the lens, both protected by patents filed during the ERC AdG.The Light-AIOL ERC-Proof of Concept aims at evaluating the marketability of the developed AIOL platform and at reaching a product commercialization plan to be presented to industrial and financial investors with the ultimate goal of bringing to market this technology, and move to a phase closer to deployment in patients. This should bring surgical corrections of presbyopia into a new paradigm. Ámbito científico natural scienceschemical sciencesphysical chemistryphotochemistrysocial scienceseconomics and businesseconomicsproduction economicsproductivitynatural sciencesphysical sciencesopticsnatural sciencesbiological sciencesbiophysicsengineering and technologyindustrial biotechnologybiomaterials Programa(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Tema(s) ERC-PoC-2016 - ERC-Proof of Concept-2016 Convocatoria de propuestas ERC-2016-PoC Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-POC - Proof of Concept Grant Institución de acogida AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Aportación neta de la UEn € 150 000,00 Dirección CALLE SERRANO 117 28006 Madrid España Ver en el mapa Región Comunidad de Madrid Comunidad de Madrid Madrid Tipo de actividad Research Organisations Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 150 000,00 Beneficiarios (1) Ordenar alfabéticamente Ordenar por aportación neta de la UE Ampliar todo Contraer todo AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS España Aportación neta de la UEn € 150 000,00 Dirección CALLE SERRANO 117 28006 Madrid Ver en el mapa Región Comunidad de Madrid Comunidad de Madrid Madrid Tipo de actividad Research Organisations Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 150 000,00