Objectif MwHresEP: Multi-well High-resolution Electrophysiology PlatformThe aim of this proof-of-concept project is to make initial steps in translating the high-density microelectrode array (HD-MEA) chip technology, which has been developed in the ERC project “NeuroCMOS” (AdG 267351, Subproject 1) into a commercial product. The project will be performed in collaboration with the spin-off company MaxWell Biosystems AG (http://www.mxwbio.com/) that has been founded after the NeuroCMOS project end by collaborators of the PI laboratory and a lab at Riken (Japan) with the purpose to commercialize the developed CMOS-based chip technology and software for neuroscientific research and industrial use in drug discovery and development. The initial steps undertaken in this PoC include (i) the development of a multi-well-plate prototype, suitable for drug discovery applications, that can host CMOS microelectrode arrays in each well. Moreover, we will (ii) develop the needed soft- and hardware to prove the feasibility of integrating the chip system prototype into cell-culture automation platforms, and we will work to (iii) obtain initial data from commercially available human induced-pluripotent-stem-cell (iPSC) -derived neurons. Champ scientifique medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencescomputer and information sciencessoftwaresocial sciencessociologyindustrial relationsautomation Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Thème(s) ERC-PoC-2016 - ERC-Proof of Concept-2016 Appel à propositions ERC-2016-PoC Voir d’autres projets de cet appel Régime de financement ERC-POC - Proof of Concept Grant Institution d’accueil EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Contribution nette de l'UE € 150 000,00 Adresse Raemistrasse 101 8092 Zuerich Suisse Voir sur la carte Région Schweiz/Suisse/Svizzera Zürich Zürich Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 150 000,00 Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Suisse Contribution nette de l'UE € 150 000,00 Adresse Raemistrasse 101 8092 Zuerich Voir sur la carte Région Schweiz/Suisse/Svizzera Zürich Zürich Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 150 000,00