Objectif DELTA-FLU aims to determine the key viral, host-related, and environmental factors that determine the dynamics of avian influenza (AI) in poultry and other host species, with the goal of improving prevention and control strategies against this disease. As a result of rapidly changing dynamics, AI continues to cause unexpected and devastating outbreaks in poultry in the EU, as well as world-wide. Its potential to become pandemic is also of great concern to public health. The key viral, host-related, and environmental factors that drive AI dynamics are poorly understood, which currently impedes the development of effective control and prevention strategies. As the problems caused by AI require global solutions, DELTA-FLU is a consortium with top-level experts from Europe, North America, and Asia. Through interdisciplinary research focused on key questions of AI, DELTA-FLU will determine 1) potential for some highly pathogenic avian influenza viruses (HPAIV, e.g. H5N8 clade 2.3.4.4) to be maintained in wild bird populations and spread over long-distances, 2) key viral, host, and environmental factors for incursion of HPAIV from wild birds into poultry holdings, 3) roles of viral, host, and environmental factors in the transition of low pathogenic avian influenza virus to HPAIV in poultry, 4) effect of flock immunity against AI on early detection and viral genetic drift, and 5) viral genetic factors that allow reassortants of avian and mammalian influenza viruses to transmit efficiently among pigs. Primary sectors and end-users are involved through participation in the Multi-Actor Panel, which will also play an important role in the translation of the results into effective prevention and control strategies. As such, DELTA-FLU will make significant advances in knowledge of AIV dynamics and provide the evidence base for improved diagnosis, prevention, and control strategies for AI in poultry, as well as for reducing the possible risk of AI to become potentially pandemic. Champ scientifique natural sciencesbiological scienceszoologyornithologynatural sciencesbiological sciencesmicrobiologyvirologymedical and health scienceshealth sciencespublic healthepidemiologypandemicsmedical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenzamedical and health sciencesbasic medicineimmunology Mots‑clés influenza poultry pigs wild birds biosecurity viral evolution interdisciplinary research long-distance spread environmental niche next-generation sequencing animal tracking Programme(s) H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy Main Programme H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience Thème(s) SFS-14-2016 - Understanding host-pathogen-environment interactions Appel à propositions H2020-SFS-2016-2017 Voir d’autres projets de cet appel Sous appel H2020-SFS-2016-2 Régime de financement RIA - Research and Innovation action Coordinateur FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT Contribution nette de l'UE € 1 425 000,00 Adresse SUDUFER 10 17493 Greifswald-Insel Riems Allemagne Voir sur la carte Région Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald Type d’activité Research Organisations Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 1 425 000,00 Participants (8) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Pays-Bas Contribution nette de l'UE € 1 187 500,00 Adresse DR MOLEWATERPLEIN 40 3015 GD Rotterdam Voir sur la carte Région West-Nederland Zuid-Holland Groot-Rijnmond Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 1 187 500,00 THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS Royaume-Uni Contribution nette de l'UE € 687 500,00 Adresse SEACOLE BUILDING, 2 MARSHAM STREET SW1P 4DF LONDON Voir sur la carte Région London Inner London — West Westminster Type d’activité Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 687 500,00 ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE Italie Contribution nette de l'UE € 625 000,00 Adresse VIALE DELL UNIVERSITA 10 35020 Legnaro Voir sur la carte Région Nord-Est Veneto Padova Type d’activité Other Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 625 000,00 UNIVERSITEIT GENT Belgique Contribution nette de l'UE € 524 611,25 Adresse SINT PIETERSNIEUWSTRAAT 25 9000 Gent Voir sur la carte Région Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 524 611,25 THE UNIVERSITY OF EDINBURGH Royaume-Uni Contribution nette de l'UE € 524 385,00 Adresse OLD COLLEGE, SOUTH BRIDGE EH8 9YL Edinburgh Voir sur la carte Région Scotland Eastern Scotland Edinburgh Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 524 385,00 LINNEUNIVERSITETET Suède Contribution nette de l'UE € 523 797,50 Adresse LINNAEUS UNIVERSITY 35195 Vaxjo Voir sur la carte Région Södra Sverige Småland med öarna Kronobergs län Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 523 797,50 THE UNIVERSITY OF HONG KONG Hong Kong Contribution nette de l'UE € 0,00 Adresse Pokfulam Road Pokfulam Voir sur la carte Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total Aucune donnée UNITED STATES DEPARTMENT OF AGRICULTURE États-Unis Contribution nette de l'UE € 0,00 Adresse Independence Ave. S.W. 1400 DC 20250 Washington Voir sur la carte Type d’activité Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Liens Contacter l’organisation Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total Aucune donnée
