Objective The field of Micro and Nano Robotics has made impressive strides over the past decade as researchers have created a variety of small devices capable of locomotion within liquid environments. Robust fabrication techniques have been developed, some devices have been functionalized for potential applications, and therapies are being actively considered. While excitement remains high for this field, we are facing a number of significant challenges that must be addressed head-on if continued progress towards clinical relevance is to be made. This project will address what we consider to be primary roadblocks to be overcome. This includes the development of bioerodable and non-cytotoxic microrobots, development of autonomous devices capable of self-directed targeting, catheter-based delivery of microrobots near the target, tracking and control of swarms of devices in vivo, and the pursuit of clinically relevant therapies. As we consider these advances, it becomes clear that the field of micro and nanorobotics is moving away from hard microfabricated structures and towards soft, polymeric structures capable of shape modification induced by environmental conditions and other “smart” behaviors. Just as the field of robotics witnessed the emergence of “soft robotics” in which soft and deformable materials are used as primary structural components, the field of microrobotics is beginning to experience a move towards “soft microrobots.” Soft microrobots are made of soft, deformable materials capable of sensing and actuation and have the potential to exhibit behavioral response. As we develop more complex soft microrobots, we are poised to realize intelligent microrobots that autonomously respond to their environment to perform more complex tasks. This project will develop a number of fundamental technologies required for the fabrication of intelligent soft microrobots suitable for in vivo applications. Animal trials and preclinical studies will be performed. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringroboticssoft robotics Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-2016-ADG - ERC Advanced Grant Call for proposal ERC-2016-ADG See other projects for this call Funding Scheme ERC-ADG - Advanced Grant Host institution EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Net EU contribution € 2 500 000,00 Address Raemistrasse 101 8092 Zuerich Switzerland See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 2 500 000,00 Beneficiaries (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Switzerland Net EU contribution € 2 500 000,00 Address Raemistrasse 101 8092 Zuerich See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 2 500 000,00