Objectif "The worldwide in vitro diagnostic (IVD) is continually growing. At least 36% of the IVD market comprises point-of-care (POC)tests, which are performed by healthcare professional in various settings or by patients themselves. A large number ofcompanies entered the POC testing market in the recent years while bringing significant technological improvements andnovel concepts to this market. Yet, many important needs for immunodiagnostics are unmet: POC tests still require relativelylarge volumes of samples, cannot readily be multiplexed, are not always accurate, and often involve simple liquiddisplacement ""from point A to point B"" with minimal control over the distribution of reagents and kinetics of reactions.Here, we propose a synergistic project aiming at developing simple-to-use and high-performance microfluidic capillarysystems (""CAPSYS"") for POC testing. Each part of the project will correspond to a complete PhD work with specific skills,methodology, and know-how from the academic and industrial PIs. The common theme for both projects will be the use ofcapillary forces for the autonomous filling of microfluidics by samples and liquids and the integration of reagents andreceptors for analyte detection inside the microfluidic chips. Those microfluidic chips will allow 1-step assays, i.e. assayswherein a non-technical user only needs to load a sample to the chip for performing a biological test.CAPSYS will lead to a new state of the art in terms of POC testing with significant relevance in medicine and diagnostics.CAPSYS will therefore be ideal for early stage researchers (ESRs) in terms of learning various disciplines in depth, creatingnumerous opportunities for publishing, and working on problem-oriented research that can have an impact in the ""realworld""." Champ scientifique natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidics Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Thème(s) MSCA-ITN-2017 - Innovative Training Networks Appel à propositions H2020-MSCA-ITN-2017 Voir d’autres projets de cet appel Régime de financement MSCA-ITN-EID - European Industrial Doctorates Coordinateur KARLSRUHER INSTITUT FUER TECHNOLOGIE Contribution nette de l'UE € 235 371,12 Adresse KAISERSTRASSE 12 76131 Karlsruhe Allemagne Voir sur la carte Région Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 235 371,12 Participants (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire IBM RESEARCH GMBH Suisse Contribution nette de l'UE € 279 961,58 Adresse SAEUMERSTRASSE 4 8803 Rueschlikon Voir sur la carte Région Schweiz/Suisse/Svizzera Zürich Zürich Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 279 961,58