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Development of novel systems for plant protection against fungal infection through genetic engineering of plants and mycoparasitic fungi

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The present proposal considers the development of novel strategies to control plant diseases caused by fungi. Such strategies would involve the use of naturally occurring systems with potential antifungal activity. The development of these novel tools will help in the reduction of the heavy economical losses reported every year as consequence of plant diseases caused by fungi. In addition, leading to a reduction in the use of chemicals.
The project involves a systematic study of two systems with potential for the control of fungal diseases. The natural plant defense response, at the gene organization and expression levels, of the so called pathogenesis related proteins (PR) and the production of mycolytic enzymes by the biocontrol agent Trichoderma spp.
Upon characterization of the corresponding genes the plant ones will be expressed in Trichoderma under the control of different fungal expression Signals and genes of fungal origin will be fused to the appropriated signals and introduced into tobacco (used as a model) and tomato plants. Due to the different biochemical characteristics of the proteins encoded by these genes it is expected to obtain plants with an improved defense system and Trichoderma strains with a better performance in biocontrol. The transgenic obtained will be tested both in vitro and in vivo for their behavior when grown in the presence of a variety of pathogenic fungi.

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CSC - Cost-sharing contracts

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Universiteit Gent
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35,K.L. Ledeganckstraat 35
9000 Gent
Belgien

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Letzte Aktualisierung: 9 Juni 1995

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Permalink: https://cordis.europa.eu/project/id/TS3*920140/de

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