Objetivo Internal parasites, especially the helminths, are one of the most important constraints to sheep and goat production and are the cause of up to 40% mortality and 38% retardation in growth of small ruminants in Southeast Asia. The control methods are limited by the high costs of anthelmintics, their uncertain availability, danger of drug resistance and limited scope for controlled grazing in communal pastoral systems. Breeding of indigenous breeds for parasite resistance coupled with animal use of anthelmintics based on epidemiological studies is an interesting long term sustainable solution to this problem. The indigenous breeds of sheep and goats managed on pastures, where they are exposed to natural infections, would be characterized for traits of productivity and parasitic burden. The parasite population within the host and on the pasture would be monitored. The impact of parasitic load on aniaml productivity in relation to host and environmental variables would be estimated. - The nucleus of flocks of sheep and goats will be constituted based on the faecal egg counts. Planned and controlled breeding will be done to segregate the animals into resistant(R), susceptible(s) and random control groups. The animals in these three lines will be characterised for production and parasitic traits. Animals of different breeds and selection lines will be subjected to experimental infection with known helminths under controlled conditions. Also the general humoral and cellular inmune competence of these animals will be evaluated using immunogens and mitogens. Various parasitological, haematological, immunological, biochemical and molecular biology techniques will be used. The analysis of data would provide information on between and within breed differences in resistance to helminths, correlations between helminth infection and productivity and epidemiology of helminth infection opening the wav for breeding for resistance and control of helminth parasites. Ámbito científico social sciencessociologydemographymortalitymedical and health scienceshealth sciencespublic healthepidemiologymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancesocial scienceseconomics and businesseconomicsproduction economicsproductivitynatural sciencesbiological sciencesmolecular biology Programa(s) FP3-STD 3 - Specific research and technological development programme (EEC) in the field of the life sciences and technologies for developing countries, 1990-1994 Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador Instituut voor Tropische Geneeskunde Prins Leopold Aportación de la UE Sin datos Dirección 155,Nationalestraat 2000 Antwerpen Bélgica Ver en el mapa Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Don Mariano Marcos Memorial State University Filipinas Aportación de la UE Sin datos Dirección Sapilang 2515 Bacnotan - La Union Ver en el mapa Coste total Sin datos Indonesia International Animal Research and Development Foundation Indonesia Aportación de la UE Sin datos Dirección 20585 Galang Ver en el mapa Coste total Sin datos Prince of Songkla University Tailandia Aportación de la UE Sin datos Dirección Hatyai, Singkhla Ver en el mapa Coste total Sin datos Universidade do Porto Portugal Aportación de la UE Sin datos Dirección S/N,Rua Dr. Roberto Frias 4200 Porto Ver en el mapa Coste total Sin datos