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Contenu archivé le 2022-12-23

Near infrared spectroscopy and imagingfor non-invasive monitoring of the oxygenation and haemodynamic status of tissues

Objectif



Optical functional imaging provides the general theoretical and methodological background for near infrared imaging.
The main tasks we propose to deal with are as follows:
1. Characterization of dynamic optical imaging of continuousprocesses. -criteria of continuity in time: time intervals should be less than time constants
-criteria of continuity in space: interpixel distance should be less than the characteristic length of cross correlation.
2. Extraction of sequences in time of optical images of prepathologic and pathologic domains by the use of dynamic contrasts of the characteristics of transient physiological processes (on the basis of a new space of space-time attributes).
3. Development of special mathematical methods and the corresponding program systems for
-space-time filtration;
-functional segmentation (like factor analysis, cluster analysis etc.). 4. Development of methods of pattern recognition of functionally normal, prepathologic and pathologic status for dynamic optical imaging of biological tissues.
5. Development of adequate space-time metric for the quantitation of dynamic images of nonstationary biological tissues. This metric can serve for the certification of new devices for optical imaging.
6. Development of methods of investigation of complementarity and supplementarity morphological and functional images
-new criteria of space resolution in functional imaging;
-localization of morphological causes of functional images.
7. Space-time modeling of haemodynamics, perfusion etc. of physiological processes of different biological tissues from the point of view of optical functional imaging. Solution of the
-"Forward Problem" for the determination of the expected images; -dynamic "Inverse Problem".

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

UNIVERSITY OF KEELE
Contribution de l’UE
Aucune donnée
Adresse
Keele University
ST5 5BG STAFFORDSHIRE
Royaume-Uni

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Coût total
Aucune donnée

Participants (3)