Objetivo Cerebrovascular disease is one of the main causes of chronic morbidity and impairment in Europe. In contrast to most countries in Western Europe, in East and Central European countries stroke mortality has increased in the past decades with stroke mortality rates ranking among the highest in the world. Furthermore, the observed increase in stroke mortality in Central and Eastern European countries remains unexplained. At present, data to explain the wide variation in stroke mortality across various European countries is very scarce. Clearly, an effective, targeted and international approach to prevent death and disability from cerebrovascular disease is hampered by this lack of knowledge. EUROSTROKE is a collaborative study among European research centres to 1) investigate the variation in incidence of fatal and non-fatal ischaemic and haemorrhagic stroke across various European countries; 2) to assess whether the difference in stroke incidence across European countries can be explained by differences in prevalence of established cardiovascular risk factors (risk factor profile) in the populations; and 3) to assess the relative importance of selected dietary factors (potassium intake, alcohol consumption, smoking), haemostatic disturbances (fibrinogen) and co-morbidity (rheumatic heart disease, mitral valve calcification, atrial fibrillation) compared to established risk factors as determinants of the occurrence of ischaemic - and haemorrhagic stroke. The EUROSTROKE database is drawn from European population based prospective follow-up studies (cohorts) and is designed as a case-control study nested within these ongoing studies. In EUROSTROKE emphasis is on a selected number of potentially modifiable risk factors, for which there is sufficient scientific evidence to foster additional research, and that may explain the wide difference in stroke mortality across countries. A further expansion of the EUROSTROKE project with a limited number of cohort studies from Central and Eastern Europe would greatly enhance the potential of the concerted action and further increase the knowledge to be gained from its conduct. The ultimate objective is to arrive at guidelines for preventive action. Programa(s) IC-PECO/COPERNICUS - Scientific and technological cooperation between the European Community and European non-member countries, 1992- Tema(s) 0201 - CEEC participation in BIOMEDICAL AND HEALTH RESEARCH programme Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador ERASMUS UNIVERSITEIT ROTTERDAM Aportación de la UE Sin datos Dirección 50,Dr. Molewaterplein 50 3015 GE ROTTERDAM Países Bajos Ver en el mapa Coste total Sin datos Participantes (2) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Institute of Internal Medicine - Russian Academy of Medical Sciences Rusia Aportación de la UE Sin datos Dirección 2A,Vladimirovsky spusk 630003 Novosibirsk Ver en el mapa Coste total Sin datos Semmelweis University of Medicine Hungría Aportación de la UE Sin datos Dirección 6,Balassa 1083 Budapest Ver en el mapa Coste total Sin datos
