Objectif A computer-based technique for long-term analysis of the sleep EEG has been developed by the Zürich group. One of the goals of the project is to make it available to the Russian group a member of which will spend time in Zürich to become familiar with the system and develop the necessary programming skills for the data analysis. The Zürich group will direct the purchase of the system which will be assembled in Moscow where it will be set up first in Dr. Kovalzon's laboratory and used for investigating putative sleep-promoting substances in rabbits. Subsequent applications will include the recording and analysis of the sleep EEG in other Russian laboratories.The Lyon group has developed a system for in vivo monitoring monoamines at specific brain sites in experimental animals. Dr. Kovalzon will spend some time in Lyon applying this technique to investigate the mechanism of action of putative sleep-promoting substances. While it is not yet feasible to transfer this method to Moscow, such a possibility is envisaged at a later stage. Since electrophysiological recordings are only exceptionally feasible in aquatic mammals, direct observation is mandatory for recording sleep behaviour. Recent direct observations of dolphins in a dolphinarium have indicated that rapid-eye movement sleep may be present in only very short episodes. In addition, both the dolphins and seals are easily disturbed by the presence of observers and by additional light during the night. Therefore it is mandatory to perform 24-hour observations without disturbing the animals. Time-lapse video recording techniques with infrared sensitive cameras and infrared illumination have been successfully applied by the Zürich group in the study of sleep behaviour of large herbivores (elephant, giraffe), and will be now applied to the study of sleep in dolphins and seals at the marine station of Utrish. Programme(s) IC-INTAS - International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993- Thème(s) 41 - General Biology Appel à propositions Data not available Régime de financement Data not available Coordinateur Universität Zürich Contribution de l’UE Aucune donnée Adresse Winterthurerstraße 190 8057 Zürich Suisse Voir sur la carte Coût total Aucune donnée Participants (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire Russian Academy of Sciences Russie Contribution de l’UE Aucune donnée Adresse 117071 Moscow Voir sur la carte Coût total Aucune donnée Université Claude Bernard Lyon 1 France Contribution de l’UE Aucune donnée Adresse 69373 Lyon Voir sur la carte Coût total Aucune donnée
