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Improved monitoring for brain dysfunction in intensive care and surgery

Objective

Develop and evaluate in the neuromonitorig domain multi-parameter hybrid biosignal interpretation (BSI) methods;
For detection of hypoxic central nervous system (CNS) dysfunction during surgery and intensive care
For early detection of multiple-organ failure (MOF) and systemic inflammatory reaction syndrome (SIRS) in intensive care To explore the usefulness of multi-modal evoked potentials (EP) in monitoring the level of sedation in intensive care.

Validate a BSI development framework (Data Library - BSI development - Clinical evaluation) in order to focus research on real clinical problems and to speed up the transfer of results into commercial products and clinical use.

The goals of IBIS are twofold. At the conceptual level, this project validates anew framework for collaboration between clinicians, industry, and biomedical engineers. At the practical level, IBIS develops, validates and evaluates new BSI methods for neuromonitoring in order to improve the outcomes of critical care. The foundation of the project is an annotated Data Library (DL) of continuous physiological signals and intermittent signals and variables of patients during intensive care and surgery. This DL will be collected at three clinical sites in the domain of neuromonitoring. Three BSI task groups each concentrating on one of the three disorder sets will use the DL. The resulting BSI methods are validated with a separate part of the DL. Those that pass will finally be evaluated in a real clinical setting. The technical basis for this approach is formed by the existing open monitoring and data management platform which will be upgraded in the project to include neurophysiological measurements. This platform is available through the participation two leading manufacturers in the IBIS consortium. In reaching its goals, the outcomes IBIS produces are:
for industry - increased product functionality and a way to play an active role in the
development of BSI methods for patient monitoring
for research - true use of BSI fusion techniques and a way to collaborate closely with industry and clinicians
for critical care - improved outcomes in critical care and a way to work with industry and research in problem formulation and assessing the value of BSI techniques.

Call for proposal

Data not available

Coordinator

Technical Research Centre of Finland
EU contribution
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Address
12B,KANSLERINKATU 12 B
33101 TAMPERE
Finland

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Total cost
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Participants (11)