Obiettivo The general objective of this program is to understand the principal mechanisms governing apoptosis or programmed cell depth, both in normal cells and in cancer cells, to unravel differences in physiology and pathology of cell death regulation, and to design novel strategies for the correction of disease-associated imbalances in cell death regulation. In particular, we are interested in understanding how cancer cells become apoptosis resistant and how this resistance can be overcome. A consortium of 11 leading research teams from 7 different countries will identify and characterize novel cell death inducing or cell death inhibitory pathways via a multidisciplinary approach integrating advanced technologies of Molecular and Cellular Biology. In addition, the group will monitor cancer cells for alterations in such cell death modulator pathways, and manipulate them to kill chemotherapy-resistant tumour cells. Campo scientifico medical and health sciencesclinical medicineoncologymedical and health sciencesbasic medicinepathologymedical and health sciencesbasic medicinephysiology Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Contributo UE Nessun dato Indirizzo Rue Guy Môquet 19 94801 Villejuif Francia Mostra sulla mappa Costo totale Nessun dato Partecipanti (10) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Francia Contributo UE Nessun dato Indirizzo Parc Scientifique et Technologique de Luminy 13288 MARSEILLE Mostra sulla mappa Costo totale Nessun dato FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW Belgio Contributo UE Nessun dato Indirizzo Rijvisschestraat 120 9052 ZWIJNAARDE Mostra sulla mappa Costo totale Nessun dato GERMAN CANCER RESEARCH CENTER Germania Contributo UE Nessun dato Indirizzo Im Neuenheimer Feld 280 69120 HEIDELBERG Mostra sulla mappa Costo totale Nessun dato INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Francia Contributo UE Nessun dato Indirizzo Parc Scientifique de Luminy 13288 MARSEILLE Mostra sulla mappa Costo totale Nessun dato MEDICAL RESEARCH COUNCIL Regno Unito Contributo UE Nessun dato Indirizzo Lancaster Road University of Leicester Hodgkin Bui LE1 9HN Leicester Mostra sulla mappa Costo totale Nessun dato THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Regno Unito Contributo UE Nessun dato Indirizzo Trinity Lane, The Old Schools, CB2 1TN CAMBRIDGE Mostra sulla mappa Costo totale Nessun dato THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN HEREINAFTER TRINITY COLLEGE DUBLIN Irlanda Contributo UE Nessun dato Indirizzo Trinity College 2 DUBLIN Mostra sulla mappa Costo totale Nessun dato UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA Italia Contributo UE Nessun dato Indirizzo VIA ORAZIO RAIMONDO 18 ROMA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato University of Ulm Germania Contributo UE Nessun dato Indirizzo Albert-Einstein-Allee 11 89070 Ulm Mostra sulla mappa Costo totale Nessun dato WEIZMANN INSTITUTE OF SCIENCE Israele Contributo UE Nessun dato Indirizzo Herzel Street 2 P.O.Box 26 REHOVOT Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato