Obiettivo To unravel the molecular mechanisms underlying proper mammalian development is one of the most pressing tasks for modern biomedical science. The complicated processes leading to genetic disease can only be understood, if we comprehend normal development. To study differentiation processes we have decided to focus on the development of the go- and, which is widely believed to be the best model system. We are planning to elucidate differentiation on a molecular level using a variety of approaches. In vitro studies will be performed to define interactions between known factors. Transgenic and knock-out animals will be generated to analyse gene function in an in vivo environment. Positional cloning of genes from patients with sex-reversal phenotypes will be used to identify new players in the explore patterns of evaluation in this highly diverged system. Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-8. - Research into genomes and diseases of genetic origin Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore UNIVERSITY OF NEWCASTLE UPON TYNE Contributo UE Nessun dato Indirizzo Central Parkway NE1 3BZ NEWCASTLE UPON TYNE Regno Unito Mostra sulla mappa Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Francia Contributo UE Nessun dato Indirizzo Rue de la Cardonille 141 34396 MONTPELLIER Mostra sulla mappa Costo totale Nessun dato MEDICAL RESEARCH COUNCIL Regno Unito Contributo UE Nessun dato Indirizzo Crewe Road Western General Hospital EH4 2XU EDINBURGH Mostra sulla mappa Costo totale Nessun dato UNIVERSITA DEGLI STUDI DI PAVIA Italia Contributo UE Nessun dato Indirizzo Via Forlanini 14 27100 PAVIA Mostra sulla mappa Costo totale Nessun dato