Objetivo Our aim is to provide novel antibacterials for human and animal infections therapy. Cell division and cell wall biosynthetic proteins, used as targets, will configure assays for screening natural product, synthetic compound, and "biased" chemical libraries to select candidate molecules for development as novel antibiotics. We will investigate the biochemical activities of, and obtain protein structures for, the targeted proteins to provide structure-activity relationship data for the chemical optimisation of lead compounds. The project integrates the production of new knowledge, from the application of innovative technologies (genomics, bioinformatics, structural biology, screening technologies), to provide improved healthcare products. Participation of two leading pharmaceutical companies guarantees a link between the generation of new knowledge and the ability to exploit the results for the benefit of the end consumer. Ámbito científico natural sciencesbiological sciencesgeneticsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsnatural sciencesbiological sciencesmolecular biologystructural biology Programa(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Tema(s) 1.1.1.-12. - Biomedical ethics and bioethics in the context of respect for fundamental human values Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador UNIVERSITAET HANNOVER Aportación de la UE Sin datos Dirección Welfergarten 1 B 30167 HANNOVER Alemania Ver en el mapa Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo CENTRO DE INVESTIGACAO SOBRE ECONOMIA PORTOGUESA Portugal Aportación de la UE Sin datos Dirección RUA MIGUEL LUPI 20 1200-725 LISBOA Ver en el mapa Coste total Sin datos UNIVERSIDAD DE LA RIOJA España Aportación de la UE Sin datos Dirección AVENIDA DE LA PAZ 93 26006 LOGRONO Ver en el mapa Coste total Sin datos UNIVERSITÉ DE PARIS-NORD XIII Francia Aportación de la UE Sin datos Dirección Avenue Jean-Baptiste Clément 93430 VILLETANEUSE Ver en el mapa Coste total Sin datos University of York Reino Unido Aportación de la UE Sin datos Dirección Heslington YORK Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos
