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Biodegradable bone substitute from cultivated marine algae enriched with bone growth factors

Objective

The project addresses the problem of bone defect treatment. Using a marine alga ashydroxyapatite (HA) source, we aim to produce a fully biodegradable, bone growth-enhancing product, which can be used in any part of the skeleton to restore fully functional bones. This implant will be complete resorted and replaced by patients own, newly grown bone after a maximal period of 10 month, depending on the size of the implant. The main objectives are: - Cultivating the alga to ensure a permanent and high quality supply- Standardise the transformation process and develop a compacted form for more complicated areas- Integrate the HA in a carrier to simplify the application- Enrich the HA/carrier complex with bone growth factor and other medicines for long term release Prototype products will be tested on animals and humans equally, after ethical and legal considerations.

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