Objective Foreseen ResultsJoint analysis on Czech and French miners with low annual exposure to radon dicey products:- end of 1997 : validation of dosimetric history of each of the 5000 Czech miners and 4000 French miners. Description of the distribution of concomittant exposures to gamma radiation and to ore dust.- 1998 and 1999 : analysis of dose-response relationship between cumulative exposure and lung cancer risk, influence of dose-rate effect, of gamma and ore dust exposure.- 1997-1998 : validation of the data concerning the domestic radon study.Epidemiological cohort studies on French and Czech uranium miners have been published recently : they demonstrate a clear increase of lung cancer mortality with increasing cumulated radon exposure. Other components; more or less linked to this cumulated exposure have been tested : duration of exposure, dose-rate, age since first or last exposure. The way how this cumulated exposure has been protracted over time and how it may influence the dose-response relationship is one of the major points of our collaborative studies. Czech and French uranium miners have experienced different radon concentrations in uranium mining, and we will be able to study the risk down to less than 1 WLM per year; history of exposure shows that exposure levels have changed in time and those miners having experienced low exposure per year, have entered later the mines and are younger than those having experienced high annual exposures. Taking in account these time dependent variables linked both to exposure and to risk are one of the main methodological objectives of these cohort studies. Parallel to the uranium miners studies, an exchange of experience between the three partners will be organized in order to favor the study of domestic radon in Czech republic; a cohort study, organized in high exposed regions like Bohemia, will be discussed, in order to test the possibility of including it in the joint European analysis planned for the next years. Fields of science natural scienceschemical sciencesinorganic chemistrynoble gasessocial sciencessociologydemographymortalityhumanitieshistory and archaeologyhistorymedical and health sciencesclinical medicineoncologylung cancersocial sciencespolitical sciencesgovernment systems Programme(s) FP4-INCO - Specific research, technological development and demonstration programme in the field of cooperation with third countries and international organizations, 1994-1998 Topic(s) 01020303 - Health consequences of radiation exposure Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator COMMISSARIAT A L'ENERGIE ATOMIQUE EU contribution No data Address 60-68,Avenue du General Leclerc 60-68, Batiment 25 92265 FONTENAY AUX ROSES France See on map Total cost No data Participants (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all Imperial Cancer Research Fund United Kingdom EU contribution No data Address The Radcliffe Infirmary, Gibson Building OX2 6HE Oxford See on map Total cost No data National Radiation Protection Institute Czechia EU contribution No data Address 48,Srobarova 100 00 Praha 10 See on map Total cost No data