Objectif The project will investigate systematic and random errors associated with the A-bomb dosimetry, and assess their impact on cancer risk estimates. Fast neutron fluences in Hiroshima will be determined retrospectively by extremely sensitive accelerator mass spectrometry, to reassess neutron doses of the A-bomb survivors (LSS cohort), and resolve thereby the' neutron discrepancy' in Hiroshima, which is currently one of the major sources of uncertainty in the derivation of risk coefficients. The results will, together with updated information on y-ray dosimetry, serve as the basis for an appraisal of the impact of dosimetric changes and dosimetric random errors on risk coefficients for y-rays and neutrons and on their Lincertainties. Sources of uncertainty in the LSS other than systematic errors in Hiroshima neutron dose estimates, such as different types of random errors in dose estimates, and modelling uncertainties associated with projecting risks to low doses and over time, will be assessed. Consequent uncertainties in the cancer risk estimates derived from the LSS will be quantified in terms of different carcinogenesis models (empirical and mechanistic). Champ scientifique medical and health sciencesclinical medicineoncologynatural scienceschemical sciencesanalytical chemistrymass spectrometry Programme(s) FP5-EAECTP C - Research and training programme (Euratom) in the field of nuclear energy (1998 to 2002) Thème(s) 2.1.3.-4. - Internal and external dosimetry Appel à propositions Data not available Régime de financement CSC - Cost-sharing contracts Coordinateur LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH Contribution de l’UE Aucune donnée Adresse Schillerstrasse 42 80336 MUENCHEN Allemagne Voir sur la carte Coût total Aucune donnée Participants (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE Royaume-Uni Contribution de l’UE Aucune donnée Adresse Norfolk Place W2 1PG LONDON Voir sur la carte Coût total Aucune donnée NATIONAL RADIOLOGICAL PROTECTION BOARD Royaume-Uni Contribution de l’UE Aucune donnée Adresse Chilton OX11 0RQ DIDCOT,HARWELL,CHILTON Voir sur la carte Coût total Aucune donnée