Objective It is the aim of this project to engineer connective tissue in vitro and to demonstrate its applicability as a tissue substitute in vivo. To achieve this goal a continuous cultivation process based on a perfused fixed-bed bioreactor system and its components will be developed which allows the production of large quantities of three-dimensional (3-d) tissue cultures in combination with capillary-like prevascular precursors to form in vitro tissue constructs. The primary focus will be bone tissue, and bone tissue constructs will then subsequently be implanted in vivo to demonstrate their potential to improve current limitations in bone substitution surgery. Fields of science engineering and technologyenvironmental biotechnologybioremediationbioreactorsmedical and health sciencesclinical medicinesurgery Programme(s) FP5-GROWTH - Programme for research technological development and demonstration on "Competitive and sustainable growth 1998-2002" Topic(s) 1.1.3.-5. - RTD Activities of a Generic Nature : materials and their technologies for production and transformation and new and improved materials and production technologies in the steel field Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator University of Ulm EU contribution No data Address Albert-Einstein-Allee 11 89070 Ulm Germany See on map Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all BIOSCAN B.V. Netherlands EU contribution No data Address 10,Prof. Bronkhorstlaan 10 bld.D 3723 MB BILTHOVEN See on map Total cost No data CAM IMPLANTS B.V. Netherlands EU contribution No data Address Zernikedreef 6 2333 CL LEIDEN See on map Total cost No data GBF - NATIONAL CENTRE FOR BIOTECHNOLOGY Germany EU contribution No data Address Mascheroder Weg 1 38124 BRAUNSCHWEIG See on map Total cost No data MEREDOS GMBH Germany EU contribution No data Address 37,Alte Dorfstraat 37 37120 BOVENDEN See on map Total cost No data MNEMOSCIENCE GMBH Germany EU contribution No data Address Pauwelsstrasse 19 52074 AACHEN See on map Total cost No data UNIVERSITY OF AVEIRO Portugal EU contribution No data Address Campo Universitario de Santiago 3810-193 AVEIRO See on map Total cost No data UNIVERSITY OF MANCHESTER United Kingdom EU contribution No data Address Oxford Road MANCHESTER See on map Links Website Opens in new window Total cost No data UNIVERSITY OF NOTTINGHAM United Kingdom EU contribution No data Address University Park NG7 2RD NOTTINGHAM See on map Total cost No data
