Objective The incidence of cancer is increasing steadily in tissues that are regulated by estrogens. It has been proposed that the increased cancer incidence but also fertility problems in wildlife and humans is caused by an increased exposure to environmental compounds that mimic endogenous estrogens. In the current project we will perform model studies to determine the potential impact of developmental exposure to weak estrogens on the incidence of diseases in the mammary gland, testis, prostate, ovary and brain. The project aims to improve current testing strategies, and provide molecular markers that can be used in clinical research to quantify the involvement of dietary and environmental estrogens in the ethnology of major human diseases. Fields of science social sciencessociologyanthropologyethnologysocial sciencessociologydemographyfertilitymedical and health sciencesclinical medicineoncology Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-4. - Key action Environment and Health Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator NETHERLANDS INSTITUTE FOR DEVELOPMENTAL BIOLOGY EU contribution No data Address Uppsalalaan 8 3584 CT UTRECHT Netherlands See on map Total cost No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all COPENHAGEN UNIVERSITY HOSPITAL Denmark EU contribution No data Address Blegdamsvej 9 2100 KOEPENHAGEN See on map Total cost No data JOHANNES GUTENBERG UNIVERSITAET MAINZ Germany EU contribution No data Address Staudinger Weg 7 55099 MAINZ See on map Total cost No data KAROLINSKA INSTITUTE Sweden EU contribution No data Address Novum Huddinge Sjukhus 141 86 Huddinge See on map Total cost No data UTRECHT UNIVERSITY Netherlands EU contribution No data Address Sorbonnelaan 16 3584 CA UTRECHT See on map Total cost No data