Obiettivo Steroid and thyroid hormones influence brain structure and function from early development through to ageing. Their actions are mediated by nuclear hormone receptors (NR) that regulate gene transcription via association with proteins that modulate their transactivation potential (nuclear receptor co-regulators;NRC) . Little is known on NRC in the brain despite their potential importance for determining NR signalling efficacy during and specificity. This project seeks to identify novel, and characterise the significance of select NRC in brain development and function using state-of-the-art methods of molecular and cell biology. The project will contribute to cell and molecular neuroscience, and will serve in the development of more effective drugs or gene therapies for brain disorders. Campo scientifico natural sciencesbiological sciencesneurobiologymedical and health sciencesmedical biotechnologygenetic engineeringgene therapynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencescell biologynatural sciencesbiological sciencesmolecular biologymolecular neuroscience Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-9. - Neurosciences Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Contributo UE Nessun dato Indirizzo Rue Cuvier 7 75231 PARIS Francia Mostra sulla mappa Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Francia Contributo UE Nessun dato Indirizzo Rue Laurent Fries 1 67404 ILLKIRCH GRAFFENSTADEN Mostra sulla mappa Costo totale Nessun dato INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES Ungheria Contributo UE Nessun dato Indirizzo Szigony u. 43 1083 BUDAPEST Mostra sulla mappa Costo totale Nessun dato JENAPHARM GMBH & CO Germania Contributo UE Nessun dato Indirizzo Otto-Schott-Str. 15 07745 JENA Mostra sulla mappa Costo totale Nessun dato
