Objective Our goal is to study the relationship between learning ability NMDA receptor and LTP using the PSD 95 mutant mice. In vitro studies show that these mice exhibit larger LTPthan wild type. We will induce LTP in vivo on mutant and wild type mice before and after groups of both types will be subjected to a battery of spatial and non-spatial learning task. Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-4. - Key action Environment and Health Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator MRC National Institute for Medical Research EU contribution No data Address The Ridgeway Mill Hil NW7 1AA London United Kingdom See on map Total cost No data
