Objetivo I will test if ShcC-driven signalling events in postmitotic neurons are critical for neuronal viability and phenotypic stability.We will test this possibility by:1) producing mice and derive cells in which mature neurons are deleted of ShcC in a constitutive or inducible manner2) identifying promoter sequences and molicules important for ShcC expression in mature neurons3) identifying the downstream signalling events initiated by ShcC in CNS neurons Ámbito científico natural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programa(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación RGI - Research grants (individual fellowships) Coordinador The University of Edinburgh Aportación de la UE Sin datos Dirección West mains road, king's buildings EH9 3JQ Edinburgh Reino Unido Ver en el mapa Coste total Sin datos Participantes (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Not available Italia Aportación de la UE Sin datos Dirección Ver en el mapa Coste total Sin datos