Obiettivo A wide range of common and lethal pathologies such as cardiovascular diseases, tumour growth and metastatic spread, are linked to the disruption of the angiogenic balance. The antiangiogenic treatments currently in clinical trials for cancer generally target a limited number of events involved in the angiogenic process. There is a pressing need to expand the number of therapeutic targets in this area. The consortium partner laboratories contribute expertise on a wide spectrum of cellular and in vivo models, providing a comprehensive representation of specific steps in neovascularization. These models will be processed by genomics analysis and promising genes will be pre-selected in vitro. The selected genes will be assessed and compared in the set of physiological and pathological models. This strategy will lead to the identification of novel critical genes and define their role in angiogenesis. Campo scientifico natural sciencesbiological sciencesgeneticsmedical and health sciencesclinical medicinecardiologycardiovascular diseasesmedical and health sciencesclinical medicineoncologymedical and health sciencesbasic medicinepathology Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore AVENTIS PHARMA RECHERCHE DEVELOPPEMENT S.A. Contributo UE Nessun dato Indirizzo Quai Jules Guesde 13 94403 VITRY SUR SEINE Francia Mostra sulla mappa Costo totale Nessun dato Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW Belgio Contributo UE Nessun dato Indirizzo 49,Herestraat 49 KUL / Campus Gasthuisberg 3000 LOUVAIN / LEUVEN Mostra sulla mappa Costo totale Nessun dato MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. Germania Contributo UE Nessun dato Indirizzo Benekestrasse 2 61231 BAD NAUHEIM Mostra sulla mappa Costo totale Nessun dato TUMOR BIOLOGY CENTRE FREIBURG Germania Contributo UE Nessun dato Indirizzo Breisacher Strasse 117 79106 FREIBURG (IN BREISGAU) Mostra sulla mappa Costo totale Nessun dato UNIVERSITY OF HELSINKI Finlandia Contributo UE Nessun dato Indirizzo 3,Haartmaninkatu 8 00014 HELSINKI Mostra sulla mappa Costo totale Nessun dato