Objetivo Molecular Biophysics has reached the point where it can move from model system studies to a direct intracellular approach of molecular events in single livingcells.Five Laboratories of Molecular Biophysics belonging to three European Countries propose to bring together their know how in optical microspectrometries and cellular biology in order to develop this new approach at the single cell level, to push back its limits and to demonstrate on some examples its advantages over more classical biophysical or biochemical approaches.They will concentrate their efforts on the investigation of the mechanisms of action of two families of drugs used in chemotherapy and of the mechanisms of cell-cell interaction in cytotoxicity.A part of their efforts will be devoted to the introduction of new physical parameters in the analysis(time resolution, extension of the excitation wavelength range)in order to fully exploit the possibilities offered by these spectroscopies. Ámbito científico natural sciencesbiological sciencesbiophysicsnatural sciencesphysical sciencesopticsspectroscopy Programa(s) FP2-SCIENCE - Programme plan (EEC) to stimulate the international cooperation and interchange needed by European research scientists (SCIENCE), 1988-1992 Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador Institut Curie Aportación de la UE Sin datos Dirección 11 rue Pierre et Marie Curie 75231 Paris Francia Ver en el mapa Coste total Sin datos Participantes (3) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Fondazione Internazionale Biotecnologie Italia Aportación de la UE Sin datos Dirección Via Hachej 10 20129 Milano Ver en el mapa Coste total Sin datos University of Twente Países Bajos Aportación de la UE Sin datos Dirección 5,Drienerlolaan 5 7500 AE ENSCHEDE Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos Université de Reims Champagne - Ardenne Francia Aportación de la UE Sin datos Dirección 23 rue Boulard 51100 Reims Ver en el mapa Coste total Sin datos