Objective The objective is to improve hip fracture prediction in osteoporotic patients, as compared to the conventional dual X-ray absorptiornetry (DXA). Hip fractures in elderly reduce quality of life and increase morbidity and mortality. Local bone mineral density, cortical thickness and volumes, and geometrical parameters will be determined volumetrically by spiral quantitative computed tomography (QCT) using an optimised low-dose acquisition protocol. The parameters will be correlated with bone strength and fracture load in mechanical tests. Hip fracture discrimination will be investigated in 120 elderly females. Finite element models based on the QCT scans will be generated to optimise individual fracture prediction. Standardization and quality assurance will be ensured by a dedicated software and an anthropomorphic hip-phantom. Results will allow improve targeting of preventive treatments in selected patients with potentially high fracture risk. Fields of science natural sciencescomputer and information sciencessoftwaresocial sciencessociologydemographymortalityengineering and technologymedical engineeringdiagnostic imagingcomputed tomographysocial sciencessociologysocial issuessocial inequalities Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-6. - Key action The Ageing Population and Disabilities Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS EU contribution No data Address Rue Ambroise Pare 2 75475 PARIS France See on map Total cost No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution No data Address Boulevard de l'Hopital, 151 75013 PARIS See on map Total cost No data ECOLE NATIONALE SUPÉRIEURE D'ARTS ET MÉTIERS - CENTRE DE PARIS France EU contribution No data Address Boulevard de l'Hôpital 151 75013 PARIS See on map Total cost No data UNIVERSITY OF ERLANGEN-NUREMBERG Germany EU contribution No data Address 12,Krankenhausstrasse 12 91054 Erlangen See on map Total cost No data UNIVERSITY OF MANCHESTER United Kingdom EU contribution No data Address Stopford, Oxford Road M13 9PT MANCHESTER See on map Total cost No data
