Objective OSTEOPOROSIS is a common, age-related disease with a strong genetic component. With increasing age of the population, Europe is facing substantial increase inosteoporotic fractures, which account for considerable disease-burden and costs. Early identification and treatment of subjects at risk can help preventing this. Gene polymorphisms, which predispose to osteoporosis, are the most promising risk factors. The AIM of the proposal is to quantify the effect of osteoporosis risk genes, to study the influence of calcium-intake on these effects, and to study the effect of genotype on response to treatment with hormone replacement therapy. Meta-analysis of Europe's largest population studies on osteoporosis is used to detect small, but clinically important risks. The project will result in collection of osteoporosis risk-alleles with quantified risks, which will improve clinical risk-assessment for osteoporosis. Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-6. - Key action The Ageing Population and Disabilities Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator ERASMUS UNIVERSITEIT ROTTERDAM EU contribution No data Address Dr. Molewaterplein 50 3015 GE ROTTERDAM Netherlands See on map Total cost No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all AARHUS KOMMUNEHOSPITAL - AARHUS UNIVERSITY HOSPITAL Denmark EU contribution No data Address Tage Hansens Gade, 2 8000 AARHUS C See on map Total cost No data OXAGEN LIMITED United Kingdom EU contribution No data Address Milton Park, 91 OX14 4RY ABINGDON See on map Total cost No data THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution No data Address Hills Road Addenbrooke's Hospital CB2 2QQ CAMBRIDGE See on map Total cost No data UNIVERSITAIRE INSTELLING ANTWERPEN - UNIVERSITEIT ANTWERPEN Belgium EU contribution No data Address 1,Universiteitsplein 1 2610 WILRIJK (ANTWERPEN) See on map Total cost No data UNIVERSITY OF ABERDEEN United Kingdom EU contribution No data Address Polwarth Building, Foresterhill AB25 2ZD ABERDEEN See on map Total cost No data UNIVERSITY OF FLORENCE Italy EU contribution No data Address Viale Pieraccini, 6 50134 FIRENZE See on map Total cost No data UNIVERSITY OF IOANNINA Greece EU contribution No data Address University Campus 45110 IOANNINA See on map Total cost No data