Objectif The basic principles underlying tumour immunology have evolved considerably. It has been established that :(1) the normal immune system is rarely a significant barrier to tumour growth, (2) most tumours are antigenic but few spontaneous tumours are immunogenic and (3) manipulation of the immune system can result in complete tumour eradication. Although the first two principles are well established, the third has been shown in only a few cases so far. In fact, immunotherapy often fails or is otherwise inadequate even in the presence of a potent immune response. It is therefore crucial to probe (1) which properties of the immune system contribute to poor immunogenicity and how the this property can be stimulated and (2) how cancer cells present tumour-related barriers to immunotherapy. Champ scientifique medical and health sciencesclinical medicineoncologymedical and health sciencesbasic medicineimmunologyimmunotherapy Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Thème(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Appel à propositions Data not available Régime de financement ACM - Preparatory, accompanying and support measures Coordinateur SAINT SAVAS CANCER HOSPITAL Contribution de l’UE Aucune donnée Adresse Alexandras Ave 171 11522 ATHENS Grèce Voir sur la carte Coût total Aucune donnée
