Objective The Purpose of ACCY is to unravel the auxin signaling pathways that mediate the control of cell growth. The programme will focus on identifying the molecular mechanisms underlying auxin action on the cell cycle in growing cells as well as quiescent cells which re-enter into division under developmental or environmental constraints. ACCY brings together seven participants that have accumulated a wide spectrum of complementary tools and expertise for analyzing auxin signaling cascades and the plant cell cycle at the molecular, cellular and whole plant levels. The overall aim of ACCY is to improve our understanding of the genetic and molecular control of cell division by the plant growth substance auxin in various cell and plant systems using a combination of modem biochemical, genetic and molecular cell biology approaches.Three key objectives can be defined:Objective 1 : Studying the auxin signaling pathway involved in the control of cell growth - This includes the development of new tools to impair auxin action, the identification of components of auxin signal transduction and the detailed investigation of the role of the auxin binding protein 1 (ABP1) in plant developmentObjective 2: Identifying the molecular mechanisms of auxin action on the cell cycle - Identifying the cell cycle targets of auxin/ ABP1 action given that ABP1 was recently demonstrated to play a role in the control of cell cycle. In addition, cross- talk between auxin and cytokinin in the regulation of cell division will be investigated.Objective 3: Investigating the mechanisms promoting the re-entry of quiescent cells into division. The molecular mechanisms involved in the control of the transition from Go (quiescent cells) to G1 (dividing cells) will be investigated using cell suspension cultures and integrated cell systems such as dormant cambium in poplar. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencescell biology Programme(s) FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002) Topic(s) Data not available Call for proposal Data not available Funding Scheme NET - Research network contracts Coordinator CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE EU contribution No data Address Avenue de la Terrasse 1Bètiment 23 91190 GIF SUR YVETTE France See on map Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Germany EU contribution No data Address Schlaenzlestrasse 1 79104 FREIBURG See on map Total cost No data HORTICULTURE RESEARCH INTERNATIONAL United Kingdom EU contribution No data Address Wellesbourne CV35 9EF WARWICK See on map Total cost No data ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE United Kingdom EU contribution No data Address Egham Hill TW20 0EX EGHAM,SURREY See on map Total cost No data SWISS FEDERAL INSTITUTE OF TECHNOLOGY ZUERICH Switzerland EU contribution No data Address 2,Universitaetstrasse 2 8092 ZURICH See on map Total cost No data THE SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES Sweden EU contribution No data Address Goesta Skoglund St 901 83 UMEAA See on map Total cost No data University of Cambridge United Kingdom EU contribution No data Address Tennis Court Road CB2 1QT Cambridge See on map Total cost No data