Objective Beta-carotene, the source of the lipid soluble Vita and retinue acid in humans was recommended for the prevention of arteriosclerosis and cancer development. Unexpectedly , the recent three multimembers, randomised human trials revealed the weak protective effect against the increased incidence of myocardial infarction, and morbidity/mortality due to the lung cancer. Since the b-carotene is commonly used as the food colorant , the influence of its metabolites together with fatty acids (FA) derivatives (known regulators of nuclear receptors) will be investigated in the healthy and cancer human and animal cells. The possible involvement of the new classes of proteins and genes (gene clusters) will be followed by the most modern methods to determine the early markers of pathology which would serve as the new diagnostic measure for the cancer hazard determination and understanding of the food and consumer safety. Fields of science engineering and technologymaterials engineeringcolorsmedical and health sciencesclinical medicineoncologylung cancermedical and health sciencesclinical medicinecardiologycardiovascular diseasesarteriosclerosisnatural sciencesbiological sciencesbiochemistrybiomoleculeslipidsmedical and health sciencesbasic medicinepathology Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-1. - Key action Food, Nutrition and Health Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator JAGIELLONIAN UNIVERSITY EU contribution No data Address 31501 KRAKOW Poland See on map Total cost No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all KLINIKUM DER UNIVERSITAET REGENSBURG Germany EU contribution No data Address Franz Josef Strauss Allee 11 93053 REGENSBURG See on map Total cost No data ROCHE VITAMINS LTD. Switzerland EU contribution No data Address Grenzacherstrasse 124 4070 BASEL See on map Total cost No data STATE INSTITUTE FOR QUALITY CONTROL OF AGRICULTURAL PRODUCTS (RIKILT) Netherlands EU contribution No data Address Bornsesteeg 45 6700 AE WAGENINGEN See on map Total cost No data STOCKHOLM UNIVERSITET Sweden EU contribution No data Address UNIVERSITETSVAEGEN 10 10691 STOCKHOLM See on map Total cost No data UNIVERSITA POLITECNICA DELLE MARCHE Italy EU contribution No data Address Piazza Roma 22 60100 ANCONA See on map Links Website Opens in new window Total cost No data UNIVERSITAT DE LES ILLES BALEARS Spain EU contribution No data Address Ctra. Valldemossa Km. 7,5 07071 PALMA DE MALLORCA See on map Total cost No data UNIVERSITY OF SOUTHERN DENMARK - UNIVERSITY OF ODENSE Denmark EU contribution No data Address Campusvej 55 5230 ODENSE See on map Total cost No data