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The role of the plasminogen-plasmin system following experimental focal cerebral ischemia

Objective

Micro vascular integrity is crucial for secondary brain damage, especially for oedema and haemorrhage. In a mouse model of focal cerebral schema effects of various knockout genes (u-PA, t-PA, PAI-1) on the micro vascular damage are examined by immunohistochemistry, western-blot and laser co focal microscopy.

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LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH
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Marchioninistr. 15
81377 MUENCHEN
Germany

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