Objective Attempted infection can result in systemic acquired resistance (SAR)- the development throughout the plant of immunity to subsequent attack by a broad range of normally virulent pathogens. TheArabidopsis mutant defective in induced resistance 1-1 (dirl-1) exhibits wild-type local resistance toavirulent Pseudomonas syringe, but defence gene expression is abolished in distant leaves and dirl-1fails to develop SAR to virulent Pseudomonas or Peronospora parasitical. Petiole exudates experiments indicate that dirl-1 is defective in the production or transmission from the inoculated leaf of inessential mobile signal. DIR1 encodes a putative apoplectic lipid transfer protein (LTP) and we propose that DIR1 interacts with a lipid-derived molecule to promote long distance signalling. The proposed study will determine how the DIR1 protein functions and thus reveals how to enhance the capacity of plants to develop SAR. The main objectives are proposed to be the following :¿ Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencesbiochemistrybiomoleculeslipidsnatural sciencesbiological sciencesgeneticsmutationnatural scienceschemical sciencesorganic chemistryalcoholsnatural sciencesmathematicspure mathematicsmathematical analysisfunctional analysis Keywords Arabidopsis GFP LTP Petiole exudates Pseudomonas SAR dexamethasone elicitin lipid Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) MOBILITY-2.1 - Marie Curie Intra-European Fellowships (EIF) Call for proposal FP6-2002-MOBILITY-5 See other projects for this call Funding Scheme EIF - Marie Curie actions-Intra-European Fellowships Coordinator JOHN INNES CENTRE EU contribution No data Address Norwich Research Park, Colney NORWICH United Kingdom See on map Links Website Opens in new window Total cost No data
