Obiettivo Allogeneic stem cell transplantation (HSCT) is a life saving therapy for haematological disorders (leukaemia and lymphoma, inherited immune disorders, and aplastic anaemia). Over 7000 such transplants are carried out each year in Europe. However the over all survival rate after HSCT is poor (40-60%), and cure of patients is hampered by clinical complications that arise post-transplant; largely due to genetic and biological differences which exist between a given patient and donor. These differences includ e transplantation antigens (major and minor histocompatibility antigens). Pioneering research by Partners, have indicated that a number of non-HLA gene polymorphisms also affect the severity and incidence of transplant related complications. There is an urgent need to improve patient-donor matching at both the biological and genomic level which would develop HSCT beyond the current state of the art. HSCT outcomes will be improved if predictive assays, diagnostic tools and new therapeutics were developed and ultimately used by HSCT clinicians for individual patient based medicine. TRANS-NET teams have expertise in predictive bioassays, genomics, diagnostics and novel therapeutics who will train researchers in the key technologies of, mRNA expression profi ling, pathology, non-HLA immunogenetics and mechanisms of immune recognition; with the ultimate aim of applying the results of TRANS-NET in the HSCT clinical setting. TRANS-NET aims to 1) Define new biological/genomic indicators and novel therapies for th e potential development of new clinical strategies for improving the outcome and quality of life of HSCT patients. 2) Develop unique training programmes in genomics and immunobiology of transplantation and generate highly trained scientists with the abili ty to manage complex projects and understand the scientific challenges of individualised patient medicine. 3) Disseminate knowledge gained throughout the ERA and clinical HSCT centres across the EC. Campo scientifico natural sciencesbiological sciencesgeneticsmedical and health sciencesbasic medicineimmunologymedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinetransplantationmedical and health sciencesclinical medicineoncologyleukemia Parole chiave Haematopoletic Haematopoletic stem cell transplantation Haematopoletic stem cell transplantation predicitive and preventative medicine predicitive and preventative medicine stem cell transplantation Programma(i) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Argomento(i) MOBILITY-1.1 - Marie Curie Research Training Networks (RTN) Invito a presentare proposte FP6-2002-MOBILITY-1 Vedi altri progetti per questo bando Meccanismo di finanziamento EIF - Marie Curie actions-Intra-European Fellowships Coordinatore UNIVERSITY OF NEWCASTLE-UPON-TYNE Contributo UE Nessun dato Indirizzo 6 KENSINGTON TERRACE NEWCASTLE-UPON-TYNE Regno Unito Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (12) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto "BEREICH HUMANMEDIZIN" GEORG-AUGUST-UNIVERSITY GOETTINGEN Germania Contributo UE Nessun dato Indirizzo Robert-Koch-Strasse 40 GOETTINGEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato CHARLES UNIVERSITY PRAGUE Cechia Contributo UE Nessun dato Indirizzo Ovocný trh 5 PRAHA 1 Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato GSF - FORSCHUNGSZENTRUM FüR UMWELT UND GESUNDHHEIT, GMBH Germania Contributo UE Nessun dato Indirizzo Ingolstaedter Landstrasse 1 NEUHERBERG Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato HEINRICH-HEINE-UNIVERSITäT DüSSELDORF Germania Contributo UE Nessun dato Indirizzo Universitätstrasse 1 DUSSELDORF Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato HLA ET MEDECINE Francia Contributo UE Nessun dato Indirizzo Rue de l'Ecole de Medecine, 15 PARIS Mostra sulla mappa Costo totale Nessun dato KLINIKUM DER UNIVERSITäT REGENSBURG Germania Contributo UE Nessun dato Indirizzo Franz-Josef-Strauss-Strasse-Allee 11 REGENSBURG Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato MEDICAL UNIVERSITY OF VIENNA Austria Contributo UE Nessun dato Indirizzo Spitalgasse 23 VIENNA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato TECHNISCHE UNIVERSITAET MUENCHEN - KLINIKUM RECHTS DER ISAR Germania Contributo UE Nessun dato Indirizzo ISMANNINGER STR. 22 MUNICH Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (HERINAFTER CALLED TCD) Irlanda Contributo UE Nessun dato Indirizzo College Green 2 DUBLIN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITETET I OSLO Norvegia Contributo UE Nessun dato Indirizzo Problemveien 7 OSLO Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF GENEVA Svizzera Contributo UE Nessun dato Indirizzo 24 rue du General Dufour GENEVA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF GLASGOW Regno Unito Contributo UE Nessun dato Indirizzo University Avenue GLASGOW Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato