Obiettivo We intend toppling one of the most prominent paradigms in science: the diffraction resolution limit of an imaging or writing system relying on focused light. To achieve this goal we will pursue a radically new concept. We argue that effecting a reversible saturable transition with a focal intensity distribution featuring one or more local zeros should allow imaging and writing at the molecular scale. Compared to reported efforts (from our own group), the imaging and the writing shall be performed at 1000 to 1,000,000 times lower power. Unlike the established electron beam and scanning probe approaches, our technique accesses the sample's depth. Thus it will allow the non-invasive 3D-visualization of live cells and the writing of nanostructures in 3D. Imaging live cells on a macromolecular scale (<10 nm) would revolutionize our understanding of cellular function and disease. Verification of our concept will profoundly impact the field imaging and may even challenge the current multibillion efforts in nanolithography to translate optical technology into the problematical deep-UV and X-ray regime. Our endeavour does not fall into the thematic priorities of FP6. It is risky but footed on quantitative predictions. Requiring joint efforts of chemists, biologists, and physicists alike, a broadly based breaking of the diffraction barrier is a truly interdisciplinary task. Conversely, light-based nanoscopy would reflect back on these disciplines as well as on their commercial exploitation. Our success will enhance the capabilities of key industrial areas, as diverse as the biomedical industry and information technology. The project's ambition is to establish optical nanoscopy in the same way, as the scanning probe microscopes were established in the 1980's. Breaking the diffraction barrier of focusing optical systems is one of the most challenging yet realistic goals in science to date, with great potential reward. Campo scientifico natural sciencesphysical sciencesopticsmicroscopy Parole chiave Nanotechnology Risk Assessment Programma(i) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) NEST-2003-1 - Adventure activities Invito a presentare proposte FP6-2003-NEST-A Vedi altri progetti per questo bando Meccanismo di finanziamento STREP - Specific Targeted Research Project Coordinatore MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. Contributo UE Nessun dato Indirizzo Hofgartenstrasse 8 MUENCHEN Germania Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto ATTO-TEC GMBH Germania Contributo UE Nessun dato Indirizzo AM EICHENHANG 50 SIEGEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato KUNGLIGA TEKNISKA HÖGSKOLAN Svezia Contributo UE Nessun dato Indirizzo Valhallavägen 79 STOCKHOLM Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato TURUN YLIOPISTO Finlandia Contributo UE Nessun dato Indirizzo Itainen Pitkakatu, 4A TURKU Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITAET-GESAMTHOCHSCHULE-SIEGEN Germania Contributo UE Nessun dato Indirizzo HOELDERLINSTRASSE 3 SIEGEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato
