Cel The objective of the project is to develop and test an intervention to promote exclusive breastfeeding (EBF), to assess its impact on infant health in African contexts where a high prevalence of HIV is a barrier and to strengthen the evidence base regarding the optimal duration for EBF. Promotion of EBF is the most effective child health intervention currently feasible for implementation at population level in low-income countries. It can lower infant mortality by 13%, and by an additional 2% were it not for the fact that breastfeeding transmits HIV. Only recently proven to be possible in hot and even dry climates, EBF without even offering water is still little appreciated by mothers or supported by health workers. EBF rates are especially low in Africa but the potential for rapid implementation may be high. A few studies elsewhere suggest that peer counselling can often achieve dramatic increases. Thus we propose to run the first randomised trial to develop and test models for applying this approach in four African countries and to quantify health benefits, cost-effectiveness and implications for the health care system. While experts realize that the HIV threat ought not to present much of a biological constraint to promoting EBF, in heavily affected countries it does represent a cultural constraint. Overcoming this will require the development of a safe and effective means of promoting EBF that is HIV-sensitive by taking into account the need to minimise postnatal HIV transmission. Thus, this study is linked to another (funded from elsewhere) to improve methods for doing so. Another scientific constraint to the promotion of exclusive breastfeeding for six months, as recommended by WHO, is uncertainty about its impact on the micronutrient status of infants. In a substudy, we will carefully follow markers of infant micronutrient status to see how they vary by feeding pattern, including EBF, for a longer period than has been examined previously. Dziedzina nauki social sciencessociologydemographymortalitynatural sciencesbiological sciencesmicrobiologyvirologymedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVmedical and health scienceshealth sciencesnutrition Słowa kluczowe HIV era Sub-Saharan Africa breastfeeding child health child nutrition exclusive breastfeeding peer-counselling Program(-y) FP6-INCO - Specific measures in support of international cooperation: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Temat(-y) INCO-2002-A1.1 - Reproductive health Zaproszenie do składania wniosków FP6-2002-INCO-DEV-1 Zobacz inne projekty w ramach tego zaproszenia System finansowania STREP - Specific Targeted Research Project Koordynator UNIVERSITETET I BERGEN Wkład UE Brak danych Adres Muséplass 1 BERGEN Norwegia Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (6) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko CENTRE MURAZ Burkina Faso Wkład UE Brak danych Adres Avenue Mamadou Konaté BOBO-DIOULASSO Zobacz na mapie Koszt całkowity Brak danych FONDATION INSTITUT BOUISSON BERTRAND - UMR 145 - DÉPARTEMENT MALADIES INFECTIEUSES ET SANTÉ INTERNATIONALE Francja Wkład UE Brak danych Adres Parc Euromédecine, 778 rue de la Croix Verte MONTPELLIER Zobacz na mapie Koszt całkowity Brak danych MAKERERE UNIVERSITY MEDICAL SCHOOL, DEPARTMENT OF PAEDIATRICS AND CHILD HEALTH Uganda Wkład UE Brak danych Adres MULAGO HOSPITAL, DEAN's BUILDING KAMPALA Zobacz na mapie Koszt całkowity Brak danych UNIVERSITY OF THE WESTERN CAPE Republika Południowej Afryki Wkład UE Brak danych Adres Modderdam Road BELLVILLE, WESTERN CAPE Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych UNIVERSITY OF ZAMBIA, SCHOOL OF MEDICINE Zambia Wkład UE Brak danych Adres Nationalist Road LUSAKA Zobacz na mapie Koszt całkowity Brak danych UPPSALA UNIVERSITET Szwecja Wkład UE Brak danych Adres Sankt Olofsgatan 10 B UPPSALA Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych
