Obiettivo Surfaces of medical materials and devices that come into direct contact with human tissues need to be fine-tuned with regard to both physical and biological properties. A cross-disciplinary nanotechnology approach is proposed that aims to impart material surfaces with appropriate biological properties. This approach gathers competences from across Europe and includes a critical mass of resources necessary to accelerate the R&D process. The biomolecules that are to be grafted onto surfaces to functio n as nanocoatings have been selected from a class of complex polysaccharides, the pectic rhamnogalacturonans, that are known to possess anti-inflammatory properties as well as desirable physical properties. Sugar molecular structure will be altered in a controlled manner so as to favourably influence living cell behaviour around the coated materials. Current knowledge and expertise within our project team covers technologies to manufacture a range of tailored polysaccharides, to attach the molecules co valently to relevant biomaterials (e.g. titanium for dental implants) and to characterize the grafted surfaces and to assess their biocompatibility both in vitro and in vivo. We expect to generate evidence demonstrating both the antiinflammatory and mole cular flexibility of the innovative nanocoatings. This will open a platform for the development of a large range of applications that will be defined through industrial guidance and result in solutions for current bioincompatibility problems of various i mplantable devices. Industrial monitoring and engineering will allow the exploration of a wide range of applications (breast implants, meshes etc.). For one of these: the dental application, the involvement of industrial SMEs covers the full production c hain from raw material to prototype design which will lead in to a demonstration phase. Campo scientifico medical and health sciencesclinical medicineodontologydental implantologyengineering and technologynanotechnologynatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydratesmedical and health sciencesmedical biotechnologyimplantsbreast implantsengineering and technologyindustrial biotechnologybiomaterials Parole chiave Nanotechnology Programma(i) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Argomento(i) NMP-2003-3.4.2.2-3 - Intelligent' bio-materials for tissue repair and regeneration NMP-2003-3.4.1.2-1 - New knowledge on interfaces for new applications Invito a presentare proposte FP6-2003-NMP-TI-3-MAIN Vedi altri progetti per questo bando Meccanismo di finanziamento STIP - Specific Targeted Innovation Project Coordinatore DIVERGENT SA - GROUPE UTC Contributo UE Nessun dato Indirizzo Centre de Transfert - Rond Point Guy Denielou, 66 avenue de Landshut COMPIEGNE Francia Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (11) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto AGLIATI SRL Italia Contributo UE Nessun dato Indirizzo VIA STATALE BRIANTEA KM. 12,7 PALAZZAGO Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato DANISH INSTITUTE OF AGRICULTURAL SCIENCES Danimarca Contributo UE Nessun dato Indirizzo Blichers Alle 20 TJELE Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato EUROPEAN COMMISSION, JOINT RESEARCH CENTRE Belgio Contributo UE Nessun dato Indirizzo Rue de la Loi 200 BRUXELLES Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato NOBIL BIO RICERCHE S.R.L. Italia Contributo UE Nessun dato Indirizzo Strada San Rocco 36 VILLAFRANCA D'ASTI' Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato POALIS A/S Danimarca Contributo UE Nessun dato Indirizzo Bulowsvej 25 FREDERIKSBERG Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato STATICE SANTE Francia Contributo UE Nessun dato Indirizzo 9 RUE THOMAS EDISON BESANCON Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITA' DEGLI STUDI DI TRENTO Italia Contributo UE Nessun dato Indirizzo Mostra sulla mappa Costo totale Nessun dato UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE Francia Contributo UE Nessun dato Indirizzo Centre Benjamin Franklin, Rue Roger Couttolenc COMPIEGNE Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF LEEDS Regno Unito Contributo UE Nessun dato Indirizzo Woodhouse Lane LEEDS Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF OULU Finlandia Contributo UE Nessun dato Indirizzo Pentti Kaiteran katu 1 OULU Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato WAGENINGEN UNIVERSITY Paesi Bassi Contributo UE Nessun dato Indirizzo Costerweg 50 WAGENINGEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato