Objetivo Recent experiments have shown that organic material in secondary organic aerosols (SOA) can polymerize leading to new high molecular weight compounds with mass up to 1000 Da. Such polymers are of concern regarding their potential adverse health effects and impact on air quality and climate. High molecular weight compounds have been found in ambient aerosols but their origin is unknown and their identification rudimentary. This project aims to apply and develop different sophisticated analytical methods to m easure high molecular weight compounds of this SOA polymer and to characterize its chemical and physical bulk parameters. In a joint measurement campaign at a smog chamber a combined effort will be undertaken to identify and characterize these polymers pro duced from different precursors which dominate in anthropogenic and biogenic emission sources. Simultaneously, these SOA polymers will be applied on-line to cell culture systems which are representative for the inner surface of airways and/or alveoli. Part icle-cell interactions will be investigated by ultrastructural and biochemical analyses. In addition, the cell cultures will be tested for the presence of reactive oxygen species and/or (pro)inflammatory proteins. A subset of the analytical tools will be d eployed to analyse ambient samples of which selected samples will be applied to cell cultures. The project will provide a basis to assess the risk of this new category of airborne contaminants to health as well as the importance of these polymers and the p olymerization process with respect to air quality and climate change. Since European research groups are at the forefront of this new scientific development, POLYSOA will significantly raise and strengthen the capabilities and scientific competitiveness of the European Research Area in this field. Ámbito científico natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural scienceschemical sciencespolymer sciencesengineering and technologyenvironmental engineeringair pollution engineeringnatural sciencesearth and related environmental sciencesatmospheric sciencesclimatologyclimatic changes Palabras clave Cardiovascular system Environmental health Nanotechnology SOA polymer secondary organic aerosol Programa(s) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Tema(s) NEST-2003-2 - Insight activities Convocatoria de propuestas FP6-2003-NEST-B-1 Consulte otros proyectos de esta convocatoria Régimen de financiación STREP - Specific Targeted Research Project Coordinador PAUL SCHERRER INSTITUT Aportación de la UE Sin datos Dirección VILLIGEN PSI Suiza Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo CONSIGLIO NAZIONALE DELLE RICERCHE Italia Aportación de la UE Sin datos Dirección Piazzale Aldo Moro 7 ROMA Ver en el mapa Coste total Sin datos JOHANNES GUTENBERG-UNIVERSITÄT MAINZ Alemania Aportación de la UE Sin datos Dirección Saarstr. 21 MAINZ Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos TECHNISCHE UNIVERSITAET WIEN Austria Aportación de la UE Sin datos Dirección Karlsplatz 13 VIENNA Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos UNIVERSITÄT BERN Suiza Aportación de la UE Sin datos Dirección Hochschulstrasse 4 BERN Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos
