OPTOLABCARDProject reference: 16727
Funded under: FP6-NMP
Mass Produced Optical Diagnostic Labcards Based on Micro and Nano SU8 Layers [Print to PDF] [Print to RTF]
Total cost:EUR 2 975 502
EU contribution:EUR 1 649 901
Funding scheme:STREP - Specific Targeted Research Project
The emergence of new pathogens or variations has created recently severe threats to human health (E.coli O157:H7, SARS, the avian-flu disease). The gravity of the problem resides on the fact that their impact and spreading is growing dramatically due to the ongoing increase in worldwide human mobility in combination with trade in livestock, and food products. However, detecting the source of infection through conventional analytical methods requires complicated and time-consuming protocols. The project aims the development of a quick and low-cost diagnostic device (Lab on a Card) that develops and integrates technology advances in optoelectronics, microfluidic and microbiology, capable to detect, in-situ, DNA pathogens in 15 minutes.
The device consists of a hand held base unit and a cartridge or labcard that will carry out a Real Time Polymerase Chain Reaction automatically, from sample preparation to an optical detection. The labcard, made of a photo resist called SU-8, on a plastic film, contains all the disposable components, whereas the base unit includes all the standard electronics and optics. The range of applications is limitless (infectious diseases, flu, tuberculosis, hepatitis, AIDS, cancer, etc) and it will be validated on Salmonellosis and Campylobacter detection.
The scenario where this diagnostic device is used covers hospitals, food factories and private homes. Its impact will be enormous, reducing the incidence of infectious illness, and providing EU governments with a certificated tool to quickly monitor and survey the sources of pathogen contamination. An especial emphasis will be applied to develop and use micro fabrication processes that are compatible with mass production and low cost of the devices offering a protected and disruptive technology to European enterprises. The successful achievement of this project will open the door for many other analytical miniaturisations to be developed.
ARRASATE - MONDRAGON, Spain
FREDERIKSBERG C, Denmark
KGS. LYNGBY, Denmark
ST. FLORIAN AM INN, Austria